SCHEMBL35972

SCHEMBL35972

NC(=O)c1ccc(C(N)=O)c2c1CCCCCCCCCC2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 5/20 0.46
MAPK1 P28482 4/20 0.46
ALOX15 P16050 3/20 0.46
CASP1 P29466 1/20 0.46
CASP7 P55210 1/20 0.46
ALDH1A1 P00352 6/20 0.41
MAPT P10636 5/20 0.41
KDM4E B2RXH2 4/20 0.41
KMT2A Q03164 4/20 0.41
HPGD P15428 3/20 0.41
MEN1 O00255 3/20 0.41
NPC1 O15118 1/20 0.41
USP2 O75604 2/20 0.40
IKBKB O14920 1/20 0.40
TP53 P04637 1/20 0.40
MAPK10 P53779 1/20 0.40
HTR1A P08908 1/20 0.39
FABP4 P15090 1/20 0.38
TSHR P16473 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4556902 1.00 HSD17B10 (0.46) HSD17B10MAPK1ALOX15CASP1CASP7
SCHEMBL8708889 1.00 HSD17B10 (0.46) HSD17B10MAPK1ALOX15CASP1CASP7
SCHEMBL35787 1.00 HSD17B10 (0.46) HSD17B10MAPK1ALOX15CASP1CASP7
SCHEMBL5459284 1.00 HSD17B10 (0.46) HSD17B10MAPK1ALOX15CASP1CASP7
SCHEMBL16739249 1.00 HSD17B10 (0.46) HSD17B10MAPK1ALOX15CASP1CASP7
SCHEMBL919063 1.00 HSD17B10 (0.46) HSD17B10MAPK1ALOX15CASP1CASP7
SCHEMBL1160668 0.98 HSD17B10 (0.47) HSD17B10MAPK1ALOX15CASP1CASP7
SCHEMBL8362799 0.87 MAPT (0.42) HSD17B10MAPK1ALOX15CASP1CASP7
SCHEMBL6052857 0.85 HSD17B10 (0.40) HSD17B10MAPK1ALOX15CASP1CASP7
SCHEMBL472879 0.85 ALDH1A1 (0.43) HSD17B10MAPK1ALOX15CASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814517-B2 Reinforced thermoplastic moulding composition EMS-PATENT AG (CH) 2023-11-14 US claimed
CN-111253739-B DOPO derivative/carbon nanotube synergistic flame-retardant glass fiber nylon composite material 贵州省材料产业技术研究院(贵州省复合改性聚合物材料工程技术研究中心、国家复合改性聚合物材料工程技术研究中心) 2022-12-02 CN claimed
CN-111253739-A DOPO derivative/carbon nanotube synergistic flame-retardant glass fiber nylon composite material 贵州省材料产业技术研究院(贵州省复合改性聚合物材料工程技术研究中心、国家复合改性聚合物材料工程技术研究中心) 2020-06-09 CN claimed
US-20190136053-A1 POLYAMIDE MOULDING COMPOSITION AND MOULDED ARTICLE MADE THEREFROM EMS-PATENT AG (CH) 2019-05-09 US claimed
EP-3452547-A1 POLYAMIDE MOULDING COMPOSITION AND MOULDED ARTICLE MADE HEREFROM EMS-Patent AG (CH) 2019-03-13 EP claimed
EP-2029358-B1 SEMIAROMATIC POLYAMIDE COMPOSITE ARTICLE AND PROCESSES FOR ITS PREPARATION DU PONT (US) 2018-11-07 EP claimed
WO-2017191269-A1 POLYAMIDE MOULDING COMPOSITION AND MOULDED ARTICLE MADE HEREFROM EMS-PATENT AG (CH) 2017-11-09 WO claimed
EP-2307480-B1 HEAT RESISTANT THERMOPLASTIC ARTICLES INCLUDING CO-STABILIZERS DU PONT (US) 2016-08-17 EP claimed
EP-1888688-B1 THERMALLY CONDUCTIVE POLYAMIDE-BASED COMPONENTS USED IN LIGHT EMITTING DIODE REFLECTOR APPLICATIONS DU PONT (US) 2010-11-03 EP claimed
US-11993713-B2 Polyamide resin composition and method for producing same TOYOBO MC CORPORATION (JP) 2024-05-28 US disclosed
EP-3875532-B1 METALLIC-TONE THERMOPLASTIC RESIN PELLET UNITIKA LTD (JP) 2024-01-17 EP disclosed
CN-111225940-B Polymerization process 杜邦聚合物公司 2023-10-10 CN disclosed
EP-3560987-B1 GLASS FIBER-REINFORCED RESIN MOLDED ARTICLE NITTO BOSEKI CO LTD (JP) 2023-09-13 EP disclosed
US-20230174782-A1 POLYAMIDE RESIN COMPOSITION AND SLIDING MEMBER OILES CORPORATION (JP) 2023-06-08 US disclosed
US-6989198-B2 Multi-layer structure KURARAY CO., LTD. (JP) 2006-01-24 US disclosed
US-6855787-B2 A multi-layer hose having a multi-layer structure containing an inner layer made of a fluorocopolymer and an outer layer made of polyamide resin ASAHI GLASS COMPANY, LIMITED (JP) 2005-02-15 US disclosed
EP-1470910-A1 Multi-layer hose Asahi Glass Co., Ltd. (JP) 2004-10-27 EP disclosed
US-20040191440-A1 A multi-layer hose having a multi-layer structure containing an inner layer made of a fluorocopolymer and an outer layer made of polyamide resin ASAHI GLASS COMPANY LIMITED (JP) 2004-09-30 US disclosed
US-20040126523-A1 Multi-layer structure KURARAY CO., LTD., A JAPANESE CORPORATION (JP) 2004-07-01 US disclosed
US-5708125-A Process for producing precondensates of partially crystalline or amorphous, thermoplastically processable, partially aromatic polyamides or copolyamides EMS-INVENTA AG (CH) 1998-01-13 US disclosed