SCHEMBL35787

SCHEMBL35787

NC(=O)c1ccc(C(N)=O)c2c1CCCCCC2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 5/20 0.46
MAPK1 P28482 4/20 0.46
ALOX15 P16050 3/20 0.46
CASP1 P29466 1/20 0.46
CASP7 P55210 1/20 0.46
ALDH1A1 P00352 6/20 0.41
MAPT P10636 5/20 0.41
KDM4E B2RXH2 4/20 0.41
KMT2A Q03164 4/20 0.41
HPGD P15428 3/20 0.41
MEN1 O00255 3/20 0.41
NPC1 O15118 1/20 0.41
USP2 O75604 2/20 0.40
IKBKB O14920 1/20 0.40
TP53 P04637 1/20 0.40
MAPK10 P53779 1/20 0.40
HTR1A P08908 1/20 0.39
FABP4 P15090 1/20 0.38
TSHR P16473 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4556902 1.00 HSD17B10 (0.46) HSD17B10MAPK1ALOX15CASP1CASP7
SCHEMBL8708889 1.00 HSD17B10 (0.46) HSD17B10MAPK1ALOX15CASP1CASP7
SCHEMBL5459284 1.00 HSD17B10 (0.46) HSD17B10MAPK1ALOX15CASP1CASP7
SCHEMBL16739249 1.00 HSD17B10 (0.46) HSD17B10MAPK1ALOX15CASP1CASP7
SCHEMBL35972 1.00 HSD17B10 (0.46) HSD17B10MAPK1ALOX15CASP1CASP7
SCHEMBL919063 1.00 HSD17B10 (0.46) HSD17B10MAPK1ALOX15CASP1CASP7
SCHEMBL1160668 0.98 HSD17B10 (0.47) HSD17B10MAPK1ALOX15CASP1CASP7
SCHEMBL8362799 0.87 MAPT (0.42) HSD17B10MAPK1ALOX15CASP1CASP7
SCHEMBL6052857 0.85 HSD17B10 (0.40) HSD17B10MAPK1ALOX15CASP1CASP7
SCHEMBL472879 0.85 ALDH1A1 (0.43) HSD17B10MAPK1ALOX15CASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 955 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3564319-B1 POLYAMIDE RESIN COMPOSITION AND MOLDED ARTICLE PRODUCED THEREFROM LOTTE ADVANCED MAT CO LTD (KR) 2024-03-13 EP claimed
US-20240018356-A1 REINFORCED THERMOPLASTIC MOULDING COMPOSITION EMS-PATENT AG (CH) 2024-01-18 US claimed
EP-3884013-B1 DIRECT CONVERSION OF PLASTIC MATERIALS INTO METHANE AND/OR LIQUID FUELS ECOLE POLYTECHNIQUE FED LAUSANNE EPFL (CH) 2024-01-10 EP claimed
US-11814517-B2 Reinforced thermoplastic moulding composition EMS-PATENT AG (CH) 2023-11-14 US claimed
CN-115368165-A Polyamide composition and method for stacking stone slabs 财团法人石材暨资源产业研究发展中心 2022-11-22 CN claimed
CN-216055458-U Body and probe inserting structure of water quality monitoring equipment 芯视界(北京)科技有限公司 2022-03-15 CN claimed
CN-110105724-B Flame-retardant composite material and preparation method thereof 贵州省材料产业技术研究院 2021-09-28 CN claimed
US-11041047-B2 Conductive thermoplastic polyamide molding compound EMS-PATENT AG (CH) 2021-06-22 US claimed
EP-3484957-B1 CONDUCTIVE THERMOPLASTIC POLYAMIDE MOULDING MATERIAL EMS CHEMIE AG (CH) 2021-05-26 EP claimed
EP-3725833-B1 REINFORCED THERMPOLASTISCHE MOULDING COMPOSITION EMS CHEMIE AG (CH) 2021-03-17 EP claimed
EP-0159310-B1 HOLLOW COPOLYAMIDE ARTICLE HOOVER UNIVERSAL, INC (a Michigan corporation) (US) 1991-10-09 EP claimed
US-4923925-A BLENDS OF POLYAMIDES AND POLYOLEFINS MODIFIED WITH IMIDE, AMIDE, ANHYDRIDE AND ACID FUNCTIONAL GROUPS; MOLDABILITY, IMPACT RESISTANCE TORAY INDUSTRIES, INC. 1990-05-08 US claimed
EP-0193023-B1 PROCESS FOR THE PREPARATION OF COPOLYAMIDES FROM AROMATIC DICARBOXYLIC ACIDS, ADIPIC ACID AND HEXAMETHYLENE DIAMINE BAYER AG (DE) 1989-10-18 EP claimed
EP-0165022-B1 SELF-CRIMPING POLYAMIDE FILAMENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-10-18 EP claimed
EP-0154245-B1 PROCESS FOR THE FABRICATION OF COPOLYAMIDES FROM ADIPIC ACID, TEREPHTHALIC ACID AND HEXAMETHYLENE DIAMINE BAYER AG (DE) 1989-07-26 EP claimed
EP-0291833-A1 Stabilised polyamide mouldings reinforced with glass fibres BAYER AG (DE) 1988-11-23 EP claimed
EP-0291796-A1 Impact-resistant polyamide mouldings BAYER AG (DE) 1988-11-23 EP claimed
US-4777223-A IMPROVED ELONGATION, TENSILE IMPACT STRENGTH, INJECTION MOLDING UNIFORMITY AMOCO CORPORATION (US) 1988-10-11 US claimed
EP-0262796-A2 Resin compositons and their manufacturing method TORAY INDUSTRIES, INC. (JP) 1988-04-06 EP claimed
EP-0154245-A2 Process for the fabrication of copolyamides from adipic acid, terephthalic acid and hexamethylene diamine BAYER AG (DE) 1985-09-11 EP claimed