Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 8/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30781510 | 1.00 | NR1H2 (0.39) | NR1H2BRD4GABRG2GABRB3GABRA5 | |
| SCHEMBL31431751 | 0.91 | NR1H2 (0.39) | NR1H2BRD4GABRG2GABRB3GABRA5 | |
| SCHEMBL14920239 | 0.86 | BACE1 (0.41) | NR1H2GABRG2GABRB3GABRA5NR1H3 | |
| SCHEMBL24176654 | 0.84 | NR1H2 (0.36) | NR1H2BRD4GABRG2GABRB3GABRA5 | |
| SCHEMBL10299255 | 0.83 | L3MBTL1 (0.45) | NR1H2NR1H3ALDH1A1MAPTCA12 | |
| SCHEMBL7249675 | 0.82 | NR1H2 (0.43) | NR1H2BRD4GABRG2GABRB3GABRA5 | |
| SCHEMBL6120980 | 0.82 | BACE1 (0.40) | NR1H2GABRG2GABRB3GABRA5AURKA | |
| SCHEMBL18459405 | 0.82 | BRD4 (0.42) | BRD4ALDH1A1MAPT | |
| SCHEMBL4091251 | 0.81 | AURKA (0.35) | NR1H2GABRG2GABRB3GABRA5AURKA | |
| SCHEMBL481590 | 0.79 | BACE1 (0.41) | NR1H2GABRG2GABRB3GABRA5AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200140460-A1 | ANTIBACTERIAL THERAPEUTICS AND PROPHYLACTICS | VYOME BIOSCIENCES PVT. LTD. (IN) | 2020-05-07 | — | — | US | disclosed |
| US-10570152-B2 | Antibacterial therapeutics and prophylactics | VYOME THERAPEUTICS LIMITED (IN) | 2020-02-25 | — | — | US | disclosed |
| WO-2017017631-A2 | ANTIBACTERIAL THERAPEUTICS AND PROPHYLACTICS | VYOME BIOSCIENCES PVT. LTD. (IN) | 2017-02-02 | — | — | WO | disclosed |
| US-9221765-B2 | Inhibition and dispersion of bacterial biofilms with benzimidazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-12-29 | — | — | US | disclosed |
| US-20120171129-A1 | Inhibition and Dispersion of Bacterial Biofilms with Benzimidazole Derivatives | NORTH CAROLINA STATE UNIVERSITY | 2012-07-05 | — | — | US | disclosed |
| WO-2010144686-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH BENZIMIDAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2010-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120171129-A1 | Inhibition and Dispersion of Bacterial Biofilms with Benzimidazole Derivatives | SBDS, DBI, BRI3BP | NR1H2 4818/4885BRD4 205/4885GABRG2 995/4885 |
| US-20200140460-A1 | ANTIBACTERIAL THERAPEUTICS AND PROPHYLACTICS | CLPP, CFTR, ELANE | NR1H2 3032/4885BRD4 3734/4885GABRG2 3142/4885 |
| US-10570152-B2 | Antibacterial therapeutics and prophylactics | CLPP, CFTR, ELANE | NR1H2 3032/4885BRD4 3734/4885GABRG2 3142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.