Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 8/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31431751 | 0.83 | NR1H2 (0.39) | ALDH1A1NR1H2NR1H3KDM4E | |
| SCHEMBL30781510 | 0.83 | NR1H2 (0.39) | ALDH1A1NR1H2MAPTNR1H3CA12 | |
| SCHEMBL481590 | 0.83 | BACE1 (0.41) | NR1H2NR1H3 | |
| SCHEMBL14920239 | 0.83 | BACE1 (0.41) | ALDH1A1KMT2ANR1H2MAPTNR1H3 | |
| SCHEMBL2779797 | 0.83 | NR1H2 (0.39) | ALDH1A1NR1H2MAPTNR1H3CA12 | |
| SCHEMBL482090 | 0.81 | GABRG2 (0.36) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL133464 | 0.79 | ALDH1A1 (0.57) | L3MBTL1ALDH1A1KMT2ANR1H2CNR2 | |
| SCHEMBL6120980 | 0.79 | BACE1 (0.40) | L3MBTL1ALDH1A1KMT2ANR1H2MAPT | |
| SCHEMBL18459405 | 0.79 | BRD4 (0.42) | L3MBTL1ALDH1A1KMT2AMAPTGAA | |
| SCHEMBL8327704 | 0.79 | ALDH1A1 (0.42) | L3MBTL1ALDH1A1KMT2ANR1H2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9221765-B2 | Inhibition and dispersion of bacterial biofilms with benzimidazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-12-29 | — | — | US | disclosed |
| US-9221765-B2 | Inhibition and dispersion of bacterial biofilms with benzimidazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-12-29 | — | — | US | disclosed |
| US-20120171129-A1 | Inhibition and Dispersion of Bacterial Biofilms with Benzimidazole Derivatives | NORTH CAROLINA STATE UNIVERSITY | 2012-07-05 | — | — | US | disclosed |
| WO-2010144686-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH BENZIMIDAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2010-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120171129-A1 | Inhibition and Dispersion of Bacterial Biofilms with Benzimidazole Derivatives | SBDS, DBI, BRI3BP | L3MBTL1 992/4885ALDH1A1 1247/4885KMT2A 2548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.