Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | GLA | P06280 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | EGFR | P00533 | 2/20 | 0.55 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27555197 | 0.90 | MEN1 (0.56) | GAAMEN1KMT2AHSP90AA1NR3C2 | |
| SCHEMBL27778006 | 0.86 | EGFR (0.55) | GAAMEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL4254323 | 0.78 | MEN1 (0.87) | GAAMEN1KMT2AHSP90AA1NR3C2 | |
| SCHEMBL31429937 | 0.78 | MEN1 (0.82) | GAAMEN1KMT2AHSP90AA1NR3C2 | |
| SCHEMBL27883351 | 0.77 | MAOB (0.52) | MAOBNT5E | |
| SCHEMBL27798998 | 0.75 | PRKCZ (0.49) | MEN1KMT2AHSP90AA1L3MBTL1ATM | |
| SCHEMBL27955203 | 0.74 | EGFR (0.71) | GAAMEN1KMT2AHSP90AA1NR3C2 | |
| SCHEMBL19471296 | 0.74 | GAA (0.73) | GAAMEN1KMT2AHSP90AA1NR3C2 | |
| SCHEMBL27712033 | 0.74 | MAPT (0.38) | GAAMEN1KMT2ANR3C2L3MBTL1 | |
| SCHEMBL25178380 | 0.73 | MAPT (0.48) | GAAMEN1KMT2AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101691356-A | Method for synthesizing Baylis-Hillman addition compound containing 5-chloropyrazolo rings | UNIV ZHEJIANG TECHNOLOGY | 2010-04-07 | — | — | CN | disclosed |