Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | KIF11 | P52732 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | APC | P25054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27555197 | 0.81 | MEN1 (0.56) | PRKCZMAOAMAOBMEN1KMT2A | |
| SCHEMBL27778006 | 0.75 | EGFR (0.55) | MAOAMAOBMMP2MMP9MEN1 | |
| SCHEMBL27798985 | 0.75 | GAA (0.57) | MAOBMEN1KMT2AHSP90AA1ATM | |
| SCHEMBL27692151 | 0.74 | SHMT2 (0.45) | PRKCZMAOAMAOBMEN1KMT2A | |
| SCHEMBL25178380 | 0.73 | MAPT (0.48) | PRKCZMEN1KMT2AATML3MBTL1 | |
| SCHEMBL28203288 | 0.73 | MEN1 (0.38) | PRKCZMEN1KMT2AHSP90AA1ATM | |
| SCHEMBL28774867 | 0.71 | MEN1 (0.36) | PRKCZMEN1KMT2AHSP90AA1ATM | |
| SCHEMBL28091661 | 0.71 | MEN1 (0.41) | MAOAMAOBMEN1KMT2AATM | |
| SCHEMBL29051504 | 0.70 | PTGS1 (0.41) | PRKCZMEN1KMT2A | |
| SCHEMBL27712024 | 0.69 | MEN1 (0.37) | PRKCZMEN1KMT2AHSP90AA1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101691356-A | Method for synthesizing Baylis-Hillman addition compound containing 5-chloropyrazolo rings | UNIV ZHEJIANG TECHNOLOGY | 2010-04-07 | — | — | CN | disclosed |