Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28436430 | 0.87 | MAPT (0.40) | MAPTALDH1A1SMN1; SMN2HTTGAA | |
| SCHEMBL27369841 | 0.84 | ALDH1A1 (0.43) | MAPTALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL27712033 | 0.84 | MAPT (0.38) | MAPTALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL28433432 | 0.84 | MAPT (0.38) | MAPTALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL28523211 | 0.83 | KMT2A (0.47) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL29018666 | 0.81 | NR3C2 (0.41) | MAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL28158503 | 0.81 | TERT (0.35) | MAPTALDH1A1SMN1; SMN2HTTKMT2A | |
| SCHEMBL27692151 | 0.81 | SHMT2 (0.45) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28091661 | 0.81 | MEN1 (0.41) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28203288 | 0.80 | MEN1 (0.38) | MAPTALDH1A1SMN1; SMN2HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116370471-A | Composition for cerebral apoplexy | 深圳泰乐德中药有限公司 | 2023-07-04 | — | — | CN | claimed |
| CN-115746160-A | Method for reducing viscosity of polysaccharide | 南方海洋科学与工程广东省实验室(广州) | 2023-03-07 | — | — | CN | claimed |
| CN-113912596-B | Benzothiazole matrix-based palladium ion detection fluorescent probe and preparation method and application thereof | 江苏科技大学 | 2022-12-02 | — | — | CN | claimed |
| CN-113912596-A | Benzothiazole matrix-based palladium ion detection fluorescent probe and preparation method and application thereof | 江苏科技大学 | 2022-01-11 | — | — | CN | claimed |
| CN-113559097-A | Application of composition in preparation of medicine for treating amyotrophic lateral sclerosis | 江苏先声药业有限公司 | 2021-10-29 | — | — | CN | claimed |
| CN-106668006-B | Application of composition of 3-methyl-1-phenyl-2-pyrazoline-5-ketone and (+) 2-camphanol | 先声药业有限公司 | 2021-02-05 | — | — | CN | claimed |
| CN-112206229-A | Composition for treating fatty liver, hepatitis and hepatic fibrosis and its preparation method | 烟台益诺依生物医药科技有限公司 | 2021-01-12 | — | — | CN | claimed |
| CN-111788481-A | Method for analyzing 3-methyl-1-phenyl-2-pyrazolin-5-one drug substance, method for treating amyotrophic lateral sclerosis and inhibiting progression of amyotrophic lateral sclerosis, and method for producing drug containing 3-methyl-1-phenyl-2-pyrazolin-5-one drug substance | 田边三菱制药株式会社 | 2020-10-16 | — | — | CN | claimed |
| CN-108078999-B | Pharmaceutical composition for preventing and treating cerebral arterial thrombosis and preparation method and application thereof | 沈阳药科大学 | 2020-08-14 | — | — | CN | claimed |
| CN-111440181-A | Dipyrazolo seven-membered oxygen heterocyclic compound containing quinoline structure and synthetic method thereof | 烟台大学 | 2020-07-24 | — | — | CN | claimed |
| CN-111346090-A | A pharmaceutical composition | 江苏先声药业有限公司 | 2020-06-30 | — | — | CN | claimed |
| CN-111346089-A | Medicinal preparation and preparation method thereof | 江苏先声药业有限公司 | 2020-06-30 | — | — | CN | claimed |
| CN-118201611-A | Application of edaravone-containing dextroborneol composition in treatment of cognitive dysfunction | 南京宁丹新药技术有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-114539155-B | Preparation of edaravone | 江苏慧聚药业股份有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-117838686-A | Application of sparganolide B in preparing medicament for preventing or treating acne | 上海宜治生物科技有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-117843573-A | Precursor compound based on edaravone structure, and preparation method and application thereof | 郑州大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-101243050-A | Pyrazolone derivatives | HOFFMANN LA ROCHE (CH) | 2008-08-13 | — | — | CN | disclosed |
| CN-100372531-C | Percutaneous absorption preparation containing 3-methyl-1-phenyl-2-pyrazolin-5-one | LEAD CHEM CO LTD (JP) | 2008-03-05 | — | — | CN | disclosed |
| CN-100372531-C | Percutaneous absorption preparation containing 3-methyl-1-phenyl-2-pyrazolin-5-one | LEAD CHEM CO LTD (JP) | 2008-03-05 | — | — | CN | disclosed |
| CN-1694699-A | Percutaneous absorption preparations containing 3-methyl-phenyl-2-pyrazolin-5-one | LEAD CHEM CO LTD (JP) | 2005-11-09 | — | — | CN | disclosed |