Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.51 |
| ▸ | PDE5A | O76074 | 2/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.43 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2006806 | 0.88 | NR3C1 (0.42) | CYP1A2CYP17A1PDE5ASCN9ACCR1 | |
| SCHEMBL4113695 | 0.85 | CYP17A1 (0.54) | CYP1A2CYP17A1CCR1CYP11B1CYP11B2 | |
| SCHEMBL19051717 | 0.85 | CYP17A1 (0.45) | CYP1A2CYP17A1ALDH1A1TSHRCYP11B1 | |
| SCHEMBL25274445 | 0.81 | XDH (0.47) | SCN9ACCR1CYP11B1CYP11B2MAPT | |
| SCHEMBL30481229 | 0.81 | XDH (0.47) | SCN9ACCR1CYP11B1CYP11B2MAPT | |
| SCHEMBL2006080 | 0.79 | CYP11B2 (0.46) | CYP1A2CYP17A1SCN9ACCR1MEN1 | |
| SCHEMBL13791629 | 0.79 | CYP1A2 (0.62) | CYP1A2CYP17A1ALDH1A1KDM4EMEN1 | |
| SCHEMBL476793 | 0.79 | CYP1A2 (0.51) | CYP1A2CYP17A1SCN9AALDH1A1KDM4E | |
| SCHEMBL2007798 | 0.78 | CCR1 (0.41) | CYP1A2CYP17A1CCR1ALDH1A1MEN1 | |
| SCHEMBL2008964 | 0.78 | CYP11B1 (0.45) | CYP1A2CYP17A1SCN9ACCR1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679288-A | Indazoles for treating estrogen receptor beta mediated diseases | GLAXO GROUP LTD | 2010-03-24 | — | — | CN | disclosed |