SCHEMBL2779966

SCHEMBL2779966

[SiH3]O[SiH](CC(c1ccccc1)c1ccccc1)OCc1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
TACR1 P25103 2/20 0.37
IDO1 P14902 1/20 0.35
AGXT P21549 1/20 0.34
SLC6A2 P23975 2/20 0.34
SLC6A4 P31645 2/20 0.34
SLC6A3 Q01959 2/20 0.34
CA1 P00915 2/20 0.33
HTR2A P28223 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
HTT P42858 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
KCNH2 Q12809 1/20 0.32
CHRNB2 P17787 1/20 0.31
CHRNA4 P43681 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
NR4A1 P22736 1/20 0.31
NR4A2 P43354 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3157144 0.71 HTR2A (0.41) TSHRCA1HTR2ATAAR1CHRNB2
SCHEMBL18297920 0.67 TSHR (0.48) TSHRIDO1AGXTSLC6A2SLC6A3
SCHEMBL28716147 0.67 HTR2A (0.41) SLC6A2SLC6A4SLC6A3HTR2ATAAR1
SCHEMBL18389692 0.67 TAAR1 (0.47) HTR2ATAAR1
SCHEMBL2959136 0.66 TSHR (0.57) TSHRIDO1AGXTSLC6A2SLC6A3
SCHEMBL50083 0.63
SCHEMBL5029908 0.62 TSHR (0.52) TSHRIDO1AGXTSLC6A2SLC6A3
SCHEMBL106501 0.62 TSHR (0.52) TSHRIDO1AGXTSLC6A2SLC6A3
SCHEMBL1024517 0.62 TSHR (0.52) TSHRIDO1AGXTSLC6A2SLC6A3
SCHEMBL18297893 0.62 TSHR (0.52) TSHRIDO1AGXTSLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1819776-B1 AESTHETIC, STABLE CHROMATIC EMULSIONS AVON PROD INC (US) 2010-03-03 EP claimed
EP-1819776-A4 AESTHETIC, STABLE CHROMATIC EMULSIONS AVON PROD INC (US) 2008-09-10 EP claimed
US-7276553-B2 Aesthetic, stable chromatic emulsions AVON PRODUCTS, INC. (US) 2007-10-02 US claimed
EP-1819776-A2 AESTHETIC, STABLE CHROMATIC EMULSIONS AVON PRODUCTS, INC. (US) 2007-08-22 EP claimed
WO-2006065511-A2 AESTHETIC, STABLE CHROMATIC EMULSIONS AVON PRODUCTS, INC. (US) 2006-06-22 WO claimed
US-20060128883-A1 Aesthetic, stable chromatic emulsions AVON PRODUCTS, INC. 2006-06-15 US claimed
US-20240237643-A1 COMPOSITIONS WITH VIRUCIDAL AND/OR ANTIVIRAL ACTIVITY SYMRISE AG (DE) 2024-07-18 US disclosed
US-20240216248-A1 MICROBIAL GLYCOLIPIDS ANALYTICON DISCOVERY GMBH (DE) 2024-07-04 US disclosed
EP-4387587-A1 COMPOSITIONS Symrise AG (DE) 2024-06-26 EP disclosed
WO-2024110023-A1 AN ACTIVE COMPOSITION COMPRISING RETINOL SYMRISE AG (DE) 2024-05-30 WO disclosed
WO-2024110515-A1 AN ACTIVE COMPOSITION COMPRISING RETINOL SYMRISE AG (DE) 2024-05-30 WO disclosed
US-20240173227-A1 A FRAGRANCE MIXTURE CONTAINING ISOCITRONELLOL SYMRISE AG (DE) 2024-05-30 US disclosed
WO-2024104625-A1 A BLEND OF EMOLLIENTS SYMRISE AG (DE) 2024-05-23 WO disclosed
WO-2010149798-A2 USE OF POLYOLS FOR ENHANCING THE COOLING EFFECT OF A COOLING SUBSTANCE AND COOLING MIXTURES HAVING AN ENHANCED COOLING EFFECT SYMRISE AG (DE) 2010-12-29 WO disclosed
EP-1819776-B1 AESTHETIC, STABLE CHROMATIC EMULSIONS AVON PROD INC (US) 2010-03-03 EP disclosed
EP-1819776-A4 AESTHETIC, STABLE CHROMATIC EMULSIONS AVON PROD INC (US) 2008-09-10 EP disclosed
US-7276553-B2 Aesthetic, stable chromatic emulsions AVON PRODUCTS, INC. (US) 2007-10-02 US disclosed
EP-1819776-A2 AESTHETIC, STABLE CHROMATIC EMULSIONS AVON PRODUCTS, INC. (US) 2007-08-22 EP disclosed
WO-2006065511-A2 AESTHETIC, STABLE CHROMATIC EMULSIONS AVON PRODUCTS, INC. (US) 2006-06-22 WO disclosed
US-20060128883-A1 Aesthetic, stable chromatic emulsions AVON PRODUCTS, INC. 2006-06-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240216248-A1 MICROBIAL GLYCOLIPIDS UGCG, SGMS1, GPR119 TSHR 1762/4885TACR1 3483/4885IDO1 169/4885
US-20240237643-A1 COMPOSITIONS WITH VIRUCIDAL AND/OR ANTIVIRAL ACTIVITY ZC3HAV1, SAMHD1, ZC3HAV1L TSHR 4680/4885TACR1 4144/4885IDO1 861/4885
US-20240173227-A1 A FRAGRANCE MIXTURE CONTAINING ISOCITRONELLOL IPO5, OR51E2, FDFT1 TSHR 4320/4885TACR1 2188/4885IDO1 377/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.