Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | AGXT | P21549 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2959136 | 0.79 | TSHR (0.57) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL106501 | 0.75 | TSHR (0.52) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL1024517 | 0.75 | TSHR (0.52) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL18297893 | 0.75 | TSHR (0.52) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL863694 | 0.73 | TSHR (0.50) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL18297949 | 0.73 | TSHR (0.50) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL704328 | 0.71 | TSHR (0.48) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL18297894 | 0.71 | TSHR (0.48) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL7056374 | 0.71 | TSHR (0.48) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL18297920 | 0.71 | TSHR (0.48) | TSHRIDO1AGXTALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114874254-A | Method for removing trace phenyltrichloro in methyl phenyl dichlorosilane | 熵联节能科技(江苏)有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-114874254-A | Method for removing trace phenyltrichloro in methyl phenyl dichlorosilane | 熵联节能科技(江苏)有限公司 | 2022-08-09 | — | — | CN | disclosed |
| EP-2841488-B1 | LIQUID ARYL GROUP-CONTAINING POLYORGANOSILOXANE | DOW CORNING TORAY CO LTD (JP) | 2019-07-17 | — | — | EP | disclosed |
| US-9415001-B2 | Liquid aryl group-containing polyorganosiloxane | DOW CORNING TORAY CO., LTD. (JP) | 2016-08-16 | — | — | US | disclosed |
| US-20150164774-A1 | Liquid Aryl Group-Containing Polyorganosiloxane | DOW TORAY CO., LTD. (JP) | 2015-06-18 | — | — | US | disclosed |
| CN-104428347-A | Liquid aryl group-containing polyorganosiloxane | DOW CORNING TORAY CO LTD | 2015-03-18 | — | — | CN | disclosed |
| EP-2841488-A1 | LIQUID ARYL GROUP-CONTAINING POLYORGANOSILOXANE | Dow Corning Toray Co., Ltd. (JP) | 2015-03-04 | — | — | EP | disclosed |
| CN-101825734-B | Phase difference film and manufacturing method thereof | NIPPON STEEL CHEMICAL CO | 2014-08-20 | — | — | CN | disclosed |
| WO-2013161429-A1 | LIQUID ARYL GROUP-CONTAINING POLYORGANOSILOXANE | DOW CORNING TORAY CO., LTD. (JP) | 2013-10-31 | — | — | WO | disclosed |
| CN-103154095-A | Cyclosiloxane-substituted polysiloxane compounds, compositions containing the same, and methods of use thereof | BIOFILM IP LLC | 2013-06-12 | — | — | CN | disclosed |
| CN-101825734-A | Phase retardation film and manufacture method thereof | NIPPON STEEL CHEMICAL CO | 2010-09-08 | — | — | CN | disclosed |
| EP-1999167-A2 | ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR | Novolen Technology Holdings, C.V. (NL) | 2008-12-10 | — | — | EP | disclosed |
| WO-2007106348-A2 | ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR | NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) | 2007-09-20 | — | — | WO | disclosed |
| US-20070213204-A1 | Ziegler-Natta catalyst with in situ-generated donor | NOVOLEN TECHNOLOGY HOLDINGS C.V. | 2007-09-13 | — | — | US | disclosed |
| CN-1281635-C | Method for manufacturing olefin polymer | MITSUI CHEMICALS INC (JP) | 2006-10-25 | — | — | CN | disclosed |
| CN-1216916-C | Catalyst for olefin polymerization and process for producing olefin polymer using the same | MITSUI CHEMICALS INC (JP) | 2005-08-31 | — | — | CN | disclosed |
| CN-1624006-A | Method for manufacturing olefin polymer | MITSUI CHEMICALS INC (JP) | 2005-06-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150164774-A1 | Liquid Aryl Group-Containing Polyorganosiloxane | RPS3, ALOX12, MSI2 | TSHR 3359/4885IDO1 1589/4885AGXT 2220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.