Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | LPL | P06858 | 1/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.47 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.47 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.47 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.47 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL337812 | 0.84 | ACHE (0.77) | ACHETDP1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3322838 | 0.84 | CES2 (0.58) | ACHETDP1ALDH1A1LMNACES2 | |
| P-Xylene SCHEMBL28442305 | 0.82 | ACHE (0.80) | ACHETDP1ALDH1A1LMNACA2 | |
| P-Xylene SCHEMBL28540852 | 0.82 | ACHE (0.80) | ACHETDP1ALDH1A1LMNACA2 | |
| P-Xylene SCHEMBL6272681 | 0.82 | ACHE (0.80) | ACHETDP1ALDH1A1LMNACA2 | |
| P-Xylene SCHEMBL9720651 | 0.82 | ACHE (0.80) | ACHETDP1ALDH1A1LMNACA2 | |
| P-Xylene SCHEMBL28696945 | 0.82 | ACHE (0.80) | ACHETDP1ALDH1A1LMNACA2 | |
| Toluene SCHEMBL288803 | 0.82 | ACHE (0.73) | ACHETDP1ALDH1A1LMNACA2 | |
| P-Xylene SCHEMBL460348 | 0.82 | ACHE (1.00) | ACHETDP1ALDH1A1LMNACA2 | |
| P-Xylene SCHEMBL771 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8377570-B2 | Poly(arylenevinylene) and poly(heteroarylenevinylene) light emitting polymer and polymer light-emitting devices | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2013-02-19 | — | — | US | disclosed |
| US-20100016340-A1 | PHARMACEUTICAL COMPOUNDS | ASTEX THERAPEUTICS LIMITED (GB) | 2010-01-21 | — | — | US | disclosed |
| EP-1812493-A4 | POLY(ARYLENEVINYLENE) AND POLY(HETEROARYLENEVINYLENE) LIGHT EMITTING POLYMERS AND POLYMER LIGHT-EMITTING DEVICES | AGENCY SCIENCE TECH & RES (SG) | 2008-12-31 | — | — | EP | disclosed |
| US-20080272691-A1 | Poly(Arylenevinylene) and Poly(Heteroarylenevinylene) Light Emitting Polymers and Polymer Light-Emitting Devices | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2008-11-06 | — | — | US | disclosed |
| EP-1871759-A1 | BENZODIOXANE AND BENZODIOXOLANE DERIVATIVES AND USES THEREOF | Wyeth a Corporation of the State of Delaware (US) | 2008-01-02 | — | — | EP | disclosed |
| EP-1812493-A1 | POLY(ARYLENEVINYLENE) AND POLY(HETEROARYLENEVINYLENE) LIGHT EMITTING POLYMERS AND POLYMER LIGHT-EMITTING DEVICES | Agency for Science, Technology and Research (SG) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006116158-A1 | BENZODIOXANE AND BENZODIOXOLANE DERIVATIVES AND USES THEREOF | WYETH (US) | 2006-11-02 | — | — | WO | disclosed |
| US-20060241172-A1 | Benzodioxane and benzodioxolane derivatives and uses thereof | WYETH (US) | 2006-10-26 | — | — | US | disclosed |
| WO-2006049579-A1 | POLY(ARYLENEVINYLENE) AND POLY(HETEROARYLENEVINYLENE) LIGHT EMITTING POLYMERS AND POLYMER LIGHT-EMITTING DEVICES | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2006-05-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016340-A1 | PHARMACEUTICAL COMPOUNDS | PKN2, PKN1, CSNK1A1 | ACHE 3778/4885TDP1 1111/4885ALDH1A1 2942/4885 |
| US-20060241172-A1 | Benzodioxane and benzodioxolane derivatives and uses thereof | HTR2C, HTR1D, HTR1A | ACHE 969/4885TDP1 1728/4885ALDH1A1 814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.