Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL215837 | 0.82 | TDP1 (0.67) | TDP1TSHRALDH1A1HTTL3MBTL1 | |
| SCHEMBL28169538 | 0.81 | ALOX15 (0.51) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL4651104 | 0.80 | TDP1 (0.71) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL2211964 | 0.79 | ALDH1A1 (0.59) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL29453576 | 0.79 | ALDH1A1 (0.59) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL15486437 | 0.78 | ALDH1A1 (0.58) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL9820288 | 0.77 | TDP1 (0.53) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL31047331 | 0.77 | TDP1 (0.53) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL29389101 | 0.77 | ALDH1A1 (0.64) | TDP1TSHRALDH1A1CYP3A4HTT | |
| SCHEMBL212391 | 0.77 | ALDH1A1 (0.64) | TDP1TSHRALDH1A1CYP3A4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101694485-B | Method for utilizing affinity column to analyze holoprotein | UNIV SHANGHAI JIAOTONG | 2013-01-16 | — | — | CN | disclosed |
| CN-101694485-A | Method for utilizing affinity column to analyze holoprotein | UNIV SHANGHAI JIAOTONG | 2010-04-14 | — | — | CN | disclosed |