SCHEMBL27801971

SCHEMBL27801971

[CH2]CCc1cccc(F)c1Br

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 5/20 0.39
GABRA1 P14867 1/20 0.37
GABRB2 P47870 1/20 0.37
GPR84 Q9NQS5 2/20 0.36
MPO P05164 3/20 0.33
SLC6A4 P31645 3/20 0.33
IDO1 P14902 2/20 0.32
AOC3 Q16853 1/20 0.32
FFAR1 O14842 1/20 0.32
GRM2 Q14416 1/20 0.31
HPGD P15428 1/20 0.31
HTR2A P28223 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6870883 0.83 GABRA1 (0.39) TAAR1GABRA1GABRB2GPR84MPO
SCHEMBL31627734 0.81 TAAR1 (0.61) TAAR1GABRA1GABRB2MPOSLC6A4
SCHEMBL17104164 0.81 TAAR1 (0.61) TAAR1GABRA1GABRB2MPOSLC6A4
SCHEMBL28794719 0.81 TAAR1 (0.40) TAAR1GABRA1GABRB2GPR84MPO
SCHEMBL28521050 0.79 TAAR1 (0.39) TAAR1GABRA1GABRB2GPR84MPO
SCHEMBL5584389 0.78 TAAR1 (0.41) TAAR1MPOSLC6A4IDO1AOC3
SCHEMBL840509 0.78 TAAR1 (0.62) TAAR1MPOIDO1AOC3HPGD
SCHEMBL17980278 0.76 CA2 (0.39) TAAR1GABRA1GABRB2GPR84MPO
SCHEMBL30360671 0.76 CA2 (0.39) TAAR1GABRA1GABRB2GPR84MPO
SCHEMBL28528505 0.76 GABRA1 (0.46) TAAR1GABRA1GABRB2GPR84MPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101712654-A Liquid crystal compound containing fluoropyrimidine and application thereof SHIJIAZHUANG DEV ZONE YONGSHEN 2010-05-26 CN disclosed