Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | HK1 | P19367 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PARG | Q86W56 | 5/20 | 0.34 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 5/20 | 0.32 |
| ▸ | CA2 | P00918 | 5/20 | 0.32 |
| ▸ | CA9 | Q16790 | 5/20 | 0.32 |
| ▸ | CA12 | O43570 | 4/20 | 0.32 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27804432 | 0.92 | PARG (0.33) | TDP2NSD2HK1PAX8GAA | |
| SCHEMBL55489 | 0.85 | TDP2 (0.35) | TDP2NSD2HK1PAX8GAA | |
| SCHEMBL55488 | 0.75 | TDP2 (0.40) | TDP2NSD2HK1PAX8GAA | |
| SCHEMBL10775524 | 0.69 | TDP2 (0.67) | TDP2NSD2HK1PAX8GAA | |
| SCHEMBL7339146 | 0.69 | TDP2 (0.67) | TDP2NSD2HK1PAX8GAA | |
| SCHEMBL60256 | 0.68 | PARG (0.72) | MAPTPARGMEN1KMT2APKM | |
| SCHEMBL28861105 | 0.67 | SRC (0.42) | TDP2NSD2HK1PAX8GAA | |
| SCHEMBL27171469 | 0.66 | PKM (0.40) | TDP2NSD2HK1PAX8GAA | |
| SCHEMBL29902406 | 0.66 | PKM (0.62) | TDP2NSD2HK1PAX8GAA | |
| SCHEMBL6135419 | 0.65 | TDP2 (0.61) | TDP2NSD2HK1PAX8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108314663-B | Derivatives of fluorene, anthracene, xanthene, dibenzosuberone and acridine and uses thereof | 多格伍德药品公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-108314663-A | The derivative and application thereof of fluorenes, anthracene, xanthene, Dibenzosuberone and acridine | 多格伍德药品公司 | 2018-07-24 | — | — | CN | disclosed |
| CN-101730531-A | derivatives of fluorene, anthracene, xanthene, dibenzosuberone and acridine and uses thereof | AVALON PHARMACEUTICALS | 2010-06-09 | — | — | CN | disclosed |