Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.67 |
| ▸ | NSD2 | O96028 | 1/20 | 0.67 |
| ▸ | HK1 | P19367 | 1/20 | 0.67 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 12/20 | 0.55 |
| ▸ | CA1 | P00915 | 11/20 | 0.55 |
| ▸ | CA9 | Q16790 | 11/20 | 0.55 |
| ▸ | CA12 | O43570 | 10/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 6/20 | 0.50 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 5/20 | 0.48 |
| ▸ | CA6 | P23280 | 5/20 | 0.48 |
| ▸ | CA5A | P35218 | 5/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10775524 | 1.00 | TDP2 (0.67) | TDP2NSD2HK1PAX8PKM | |
| SCHEMBL29902406 | 0.95 | PKM (0.62) | TDP2NSD2HK1PAX8PKM | |
| SCHEMBL6135419 | 0.94 | TDP2 (0.61) | TDP2NSD2HK1PAX8PKM | |
| SCHEMBL20567212 | 0.92 | TDP2 (0.59) | TDP2NSD2HK1PAX8PKM | |
| SCHEMBL24312829 | 0.81 | TDP2 (1.00) | TDP2NSD2HK1PAX8PKM | |
| SCHEMBL31237278 | 0.81 | TDP2 (1.00) | TDP2NSD2HK1PAX8PKM | |
| SCHEMBL11474884 | 0.79 | PKM (0.54) | TDP2NSD2HK1PAX8PKM | |
| SCHEMBL14550508 | 0.79 | CA2 (0.50) | TDP2NSD2HK1PAX8PKM | |
| SCHEMBL11127435 | 0.79 | CA1 (0.62) | TDP2NSD2HK1PAX8PKM | |
| SCHEMBL10912858 | 0.78 | NSD2 (0.54) | TDP2NSD2HK1PAX8PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4637926-A | Method of removing hydrogen sulphide from gases | CIBA-GEIGY CORPORATION (US) | 1987-01-20 | — | — | US | claimed |
| EP-0833626-A1 | MONO- AND DISULFO-SUBSTITUTED ANTHRAQUINONES AND THEIR USE FOR THE TREATMENT OF BONE MATRIX DISORDERS | Boonville Limited (VG) | 1998-04-08 | — | — | EP | disclosed |
| WO-1997000675-A1 | MONO- AND DISULFO-SUBSTITUTED ANTHRAQUINONES AND THEIR USE FOR THE TREATMENT OF BONE MATRIX DISORDERS | BOONVILLE LIMITED (VG) | 1997-01-09 | — | — | WO | disclosed |
| US-4637926-A | Method of removing hydrogen sulphide from gases | CIBA-GEIGY CORPORATION (US) | 1987-01-20 | — | — | US | disclosed |
| EP-0008641-A1 | Anthraquinonesulphonamides and process for their manufacture | CIBA-GEIGY AG (CH) | 1980-03-19 | — | — | EP | disclosed |