SCHEMBL6135419

SCHEMBL6135419

NS(=O)(=O)c1ccc2c(c1)C(=O)c1ccccc1C2=O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP2 O95551 1/20 0.61
NSD2 O96028 1/20 0.61
HK1 P19367 1/20 0.61
PAX8 Q06710 1/20 0.61
SMN1; SMN2 Q16637 3/20 0.56
KMT2A Q03164 3/20 0.56
MAPK1 P28482 2/20 0.56
PKM P14618 2/20 0.56
MEN1 O00255 2/20 0.56
MAPT P10636 1/20 0.56
HTT P42858 1/20 0.56
NPC1 O15118 1/20 0.55
ALDH1A1 P00352 1/20 0.55
TP53 P04637 1/20 0.55
CYP3A4 P08684 1/20 0.55
TSHR P16473 1/20 0.55
RAB9A P51151 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
PARG Q86W56 5/20 0.54
BCL2 P10415 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20567212 0.98 TDP2 (0.59) TDP2NSD2HK1PAX8SMN1; SMN2
SCHEMBL7339146 0.94 TDP2 (0.67) TDP2NSD2HK1PAX8SMN1; SMN2
SCHEMBL10775524 0.94 TDP2 (0.67) TDP2NSD2HK1PAX8SMN1; SMN2
SCHEMBL29902406 0.89 PKM (0.62) TDP2NSD2HK1PAX8KMT2A
SCHEMBL27567614 0.83 KMT2A (0.59) SMN1; SMN2KMT2AMAPK1PKMMEN1
SCHEMBL14780791 0.81 BCL2 (0.62) TDP2NSD2HK1PAX8SMN1; SMN2
SCHEMBL426122 0.79 KMT2A (0.56) SMN1; SMN2KMT2AMAPK1PKMMEN1
SCHEMBL919135 0.79 KMT2A (0.56) SMN1; SMN2KMT2AMAPK1PKMMEN1
SCHEMBL9235321 0.79 PARG (0.59) SMN1; SMN2KMT2AMAPK1PKMMEN1
Potassium Ion SCHEMBL2784885 0.79 PARG (0.59) SMN1; SMN2KMT2AMAPK1PKMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1531520-A Self-reducing anthraquinone compounds �����ѧ�͹�ҵ�о���֯ 2004-09-22 CN claimed
EP-1351948-A4 NEW OXYGEN SCAVENGING COMPOSITIONS COMMW SCIENT IND RES ORG (AU) 2005-06-29 EP disclosed
US-20040099840-A1 Oxygen scavenging compositions COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2004-05-27 US disclosed
EP-1351948-A1 NEW OXYGEN SCAVENGING COMPOSITIONS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2003-10-15 EP disclosed
WO-2002051825-A1 NEW OXYGEN SCAVENGING COMPOSITIONS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2002-07-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040099840-A1 Oxygen scavenging compositions CBR1, SQOR, QSOX1 TDP2 3748/4885NSD2 4162/4885HK1 223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.