Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 14/20 | 0.62 |
| ▸ | HTR3A | P46098 | 2/20 | 0.61 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27825620 | 0.83 | MET (0.62) | METHTR3AHRH4CSF1RMEN1 | |
| SCHEMBL27804769 | 0.83 | MET (0.62) | METHTR3AHRH4GAAADRA2C | |
| SCHEMBL6352883 | 0.76 | HTR3A (1.00) | METHTR3AHRH4 | |
| SCHEMBL25970670 | 0.74 | IL2 (0.47) | METHTR3A | |
| SCHEMBL25970672 | 0.72 | HTR3A (0.44) | METHTR3AHRH4MEN1GLA | |
| SCHEMBL23761963 | 0.71 | HTR3A (0.64) | HTR3AHRH4KMT2A | |
| SCHEMBL6348984 | 0.71 | HTR3A (0.89) | METHTR3AHRH4 | |
| SCHEMBL19705439 | 0.70 | CYP1A2 (0.50) | — | |
| SCHEMBL18848439 | 0.69 | NOS1 (0.38) | — | |
| SCHEMBL20037501 | 0.68 | MAPT (0.49) | HTR3AHRH4MEN1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101993416-B | Quinoline compound and preparation method thereof, medicament combination containing compound and application of compound | SHANGHAI INST MATERIA MEDICA | 2013-09-11 | — | — | CN | disclosed |
| CN-101993416-A | Quinoline compound and preparation method thereof, medicament combination containing compound and application of compound | SHANGHAI INST MATERIA MEDICA | 2011-03-30 | — | — | CN | disclosed |