Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.46 |
| ▸ | RXRB | P28702 | 3/20 | 0.46 |
| ▸ | RXRG | P48443 | 3/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 8/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL79415 | 0.81 | RXRA (0.52) | RXRARXRBRXRGMRGPRX4S1PR1 | |
| SCHEMBL79041 | 0.78 | RXRA (0.56) | RXRARXRBRXRGMRGPRX4S1PR1 | |
| SCHEMBL18924486 | 0.76 | RXRA (0.50) | RXRARXRBRXRGMRGPRX4S1PR1 | |
| SCHEMBL6812974 | 0.76 | CYP4F2 (0.54) | RXRARXRBRXRGMRGPRX4S1PR1 | |
| SCHEMBL20756090 | 0.75 | RXRA (0.54) | RXRARXRBRXRGMRGPRX4CTSS | |
| SCHEMBL86405 | 0.75 | RXRA (0.49) | RXRARXRBRXRGMRGPRX4S1PR1 | |
| SCHEMBL656838 | 0.74 | MRGPRX4 (0.50) | RXRARXRBRXRGMRGPRX4S1PR1 | |
| SCHEMBL5388117 | 0.74 | RXRA (0.60) | RXRARXRBRXRGMRGPRX4S1PR1 | |
| SCHEMBL14453588 | 0.74 | MRGPRX4 (0.50) | RXRARXRBRXRGMRGPRX4S1PR1 | |
| SCHEMBL3726426 | 0.74 | PTGER1 (0.54) | RXRARXRBRXRGMRGPRX4SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101730677-B | Amine compound and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORP | 2014-07-16 | — | — | CN | disclosed |
| CN-101730677-A | Amine compound and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORP | 2010-06-09 | — | — | CN | disclosed |