Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.76 |
| ▸ | HTT | P42858 | 2/20 | 0.74 |
| ▸ | THRB | P10828 | 1/20 | 0.72 |
| ▸ | PKM | P14618 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2234130 | 0.87 | HPGD (1.00) | HPGDHTTTHRBPKMMEN1 | |
| Hydrochloric Acid SCHEMBL28152221 | 0.86 | HPGD (0.97) | HPGDHTTTHRBPKMMEN1 | |
| SCHEMBL2314054 | 0.86 | THRB (0.70) | HPGDHTTTHRBPKMMEN1 | |
| SCHEMBL2419952 | 0.81 | THRB (0.74) | HPGDHTTTHRBPKMMEN1 | |
| SCHEMBL14484111 | 0.79 | HPGD (0.82) | HPGDHTTTHRBPKMMEN1 | |
| SCHEMBL31236774 | 0.79 | HPGD (0.67) | HPGDHTTTHRBPKMMEN1 | |
| SCHEMBL3650142 | 0.79 | THRB (0.64) | HPGDHTTTHRBPKMMEN1 | |
| SCHEMBL29547883 | 0.78 | HPGD (0.80) | HPGDHTTTHRBPKMMEN1 | |
| SCHEMBL2305026 | 0.77 | HPGD (0.74) | HPGDHTTTHRBPKMMEN1 | |
| SCHEMBL9366252 | 0.77 | ALDH1A1 (0.58) | HPGDHTTPKMMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101784528-A | Azolorine derivatives, method for the production thereof, medicaments containing these compounds and the use thereof | SANOFI AVENTIS | 2010-07-21 | — | — | CN | disclosed |