Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ANPEP | P15144 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2780358 | 0.96 | CNR2 (0.39) | PKMTSHRSLC6A2ARCNR2 | |
| SCHEMBL2784556 | 0.88 | PKM (0.41) | PKMTSHRCNR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL2780892 | 0.84 | CNR2 (0.44) | PKMTSHRCNR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL2783111 | 0.83 | POLB (0.48) | PKMTSHRCNR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL13196451 | 0.82 | ALDH1A1 (0.39) | PKMTSHRCNR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL2782395 | 0.79 | HTT (0.39) | ARCNR2ALDH1A1POLBLMNA | |
| SCHEMBL13196442 | 0.79 | ALDH1A1 (0.41) | PKMTSHRCNR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL13196410 | 0.78 | CYP3A4 (0.42) | PKMTSHRCNR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL13196396 | 0.78 | POLB (0.40) | TSHRSLC6A2ALDH1A1L3MBTL1ANPEP | |
| SCHEMBL2782810 | 0.78 | CNR2 (0.39) | TSHRCNR2ALDH1A1L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010090680-A1 | SUBSTITUTED OXINDOLE CB2 AGONISTS | WYETH LLC (US) | 2010-08-12 | — | — | WO | claimed |