Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 7/20 | 0.43 |
| ▸ | SCD5 | Q86SK9 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27787130 | 0.90 | SCD (0.41) | SCDSCD5ALDH1A1ACACBKDM4E | |
| SCHEMBL27787111 | 0.90 | ALDH1A1 (0.41) | ALDH1A1KDM4ETSHRLMNAKMT2A | |
| SCHEMBL27808975 | 0.85 | L3MBTL1 (0.43) | SCDSCD5ALDH1A1ACACBKDM4E | |
| SCHEMBL27787096 | 0.85 | ALDH1A1 (0.42) | SCDSCD5ALDH1A1ACACBKDM4E | |
| SCHEMBL3096293 | 0.80 | NPY1R (0.43) | SCDSCD5ALDH1A1ACACBL3MBTL1 | |
| SCHEMBL3097169 | 0.78 | ALDH1A1 (0.40) | SCDSCD5ALDH1A1ACACBL3MBTL1 | |
| SCHEMBL27787149 | 0.77 | GHSR (0.44) | ALDH1A1KDM4ETSHRLMNAKMT2A | |
| SCHEMBL3092856 | 0.74 | LMNA (0.43) | ALDH1A1L3MBTL1LMNAKMT2A | |
| SCHEMBL3083807 | 0.74 | ALDH1A1 (0.43) | ALDH1A1KDM4EL3MBTL1LMNAPOLB | |
| SCHEMBL3085176 | 0.73 | NPY1R (0.41) | SCDSCD5ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101784520-A | Novel malonic acid sulfonamide derivative and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORP | 2010-07-21 | — | — | CN | disclosed |