SCHEMBL27809237

SCHEMBL27809237

CCC(CC)CN(CCO)C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
ALDH2 P05091 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9742204 0.86 ALDH1A1 (0.46) ALDH1A1
SCHEMBL871699 0.75
SCHEMBL1761184 0.74 SSTR4 (0.40)
SCHEMBL2493116 0.74 CA12 (0.41) ALDH1A1ALDH2
SCHEMBL27809294 0.73
SCHEMBL9420011 0.73 CHRNB2 (0.32)
SCHEMBL9702521 0.73 CA2 (0.44) ALDH1A1
SCHEMBL77048 0.73 CA12 (0.46) ALDH1A1ALDH2
SCHEMBL16353786 0.72 TSHR (0.33)
SCHEMBL621722 0.71 CA12 (0.39) ALDH1A1ALDH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101790529-B 8-azabicyclo [3.2.1] octyl-2-hydroxybenzamide compounds as mu opioid receptor antagonists THERAVANCE INC 2012-09-05 CN disclosed
CN-101790529-A 8-azabicyclo [3.2.1] octyl-2-hydroxybenzamide compounds as mu opioid receptor antagonists THERAVANCE INC 2010-07-28 CN disclosed