Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 11/20 | 0.40 |
| ▸ | PPARA | Q07869 | 11/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19088418 | 0.88 | L3MBTL1 (0.44) | L3MBTL1PPARGPPARAPOLBSLC6A4 | |
| SCHEMBL10875609 | 0.82 | CA1 (0.44) | SLC6A4CYP2C9TSHR | |
| SCHEMBL10875297 | 0.82 | L3MBTL1 (0.41) | L3MBTL1PPARGPPARAPOLBSLC6A4 | |
| SCHEMBL10875177 | 0.81 | PPARG (0.43) | L3MBTL1PPARGPPARAPOLBCYP1A2 | |
| SCHEMBL22644024 | 0.81 | PPARA (0.43) | L3MBTL1PPARGPPARAPOLBSLC6A4 | |
| SCHEMBL6164452 | 0.81 | ALDH1A1 (0.38) | L3MBTL1PPARGPPARASLC6A4CYP1A2 | |
| SCHEMBL7413858 | 0.80 | PPARG (0.40) | L3MBTL1PPARGPPARAPOLBSLC6A4 | |
| SCHEMBL11463800 | 0.80 | KDM4E (0.37) | PPARGPPARAPOLBSLC6A4TSHR | |
| SCHEMBL14665065 | 0.78 | LMNA (0.41) | L3MBTL1PPARGPPARAPOLBSLC6A4 | |
| SCHEMBL11162895 | 0.76 | ACACB (0.42) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102060765-A | Tetrahydroisoquinoline derivative, preparation method and application thereof | UNIV CHINA PHARMA | 2011-05-18 | — | — | CN | disclosed |