Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 3/20 | 0.42 |
| ▸ | BCR | P11274 | 3/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3664852 | 0.81 | HSD11B1 (0.41) | HSD11B1 | |
| SCHEMBL3664360 | 0.79 | LTA4H (0.43) | SLC6A7HSD11B1DHODHMETAP1 | |
| SCHEMBL3658246 | 0.79 | ALDH1A1 (0.48) | HSD11B1CNR2KDM4E | |
| SCHEMBL974424 | 0.79 | HSD11B1 (0.50) | HSD11B1 | |
| SCHEMBL3667493 | 0.77 | HSD11B1 (0.38) | HSD11B1HDAC1 | |
| SCHEMBL3666304 | 0.75 | HSD11B1 (0.42) | HSD11B1KDM4E | |
| SCHEMBL3662832 | 0.74 | HRH3 (0.43) | HSD11B1 | |
| SCHEMBL1861484 | 0.73 | HSD11B1 (0.52) | HSD11B1KDM4EHDAC1 | |
| SCHEMBL21273955 | 0.73 | SLC6A7 (0.60) | SLC6A7ABL1BCRMETAP1 | |
| SCHEMBL3664800 | 0.73 | HSD11B1 (0.56) | HSD11B1HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101981026-A | Tetrahydroquinoxaline urea derivatives, their preparation and their therapeutic use | SANOFI AVENTIS | 2011-02-23 | — | — | CN | disclosed |