Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27671499 | 0.84 | MAPT (0.44) | MAPTMEN1KMT2ATP53GAA | |
| SCHEMBL13315322 | 0.76 | PGR (0.58) | MAPTMEN1KMT2ATP53GAA | |
| SCHEMBL29077356 | 0.75 | MAPT (0.49) | MAPTMEN1KMT2ATP53GAA | |
| SCHEMBL431571 | 0.75 | NPBWR1 (0.54) | MAPTMEN1KMT2ATP53GAA | |
| SCHEMBL27809584 | 0.73 | HTR1A (0.40) | MAPTMEN1KMT2ATP53GAA | |
| SCHEMBL23409108 | 0.72 | MEN1 (0.47) | MAPTMEN1KMT2ATP53GAA | |
| SCHEMBL29741303 | 0.71 | TEAD4 (0.47) | MAPTMEN1KMT2ATP53GAA | |
| SCHEMBL8790210 | 0.71 | MAPT (0.56) | MAPTMEN1KMT2ATP53GAA | |
| SCHEMBL29741345 | 0.71 | MAPT (0.52) | MAPTMEN1KMT2ATP53GAA | |
| SCHEMBL14646364 | 0.71 | FAAH (0.43) | MEN1KMT2ASMN1; SMN2CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293808-A1 | Non-Steroidal Androgen Receptor Modulators, Preparation Process, Pharmaceutical Composition and Use Thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES (CN) | 2008-11-27 | — | — | US | claimed |
| EP-1889829-A1 | NONSTEROIC ANDROGEN ACCEPTOR REGULATORS, PREPARATION PROCESS, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2008-02-20 | — | — | EP | claimed |
| US-7737288-B2 | Non-steroidal androgen receptor modulators, preparation process, pharmaceutical composition and use thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES (CN) | 2010-06-15 | — | — | US | disclosed |
| US-7737288-B2 | Non-steroidal androgen receptor modulators, preparation process, pharmaceutical composition and use thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES (CN) | 2010-06-15 | — | — | US | disclosed |
| US-20080293808-A1 | Non-Steroidal Androgen Receptor Modulators, Preparation Process, Pharmaceutical Composition and Use Thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES (CN) | 2008-11-27 | — | — | US | disclosed |
| US-20080293808-A1 | Non-Steroidal Androgen Receptor Modulators, Preparation Process, Pharmaceutical Composition and Use Thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES (CN) | 2008-11-27 | — | — | US | disclosed |
| US-20080293808-A1 | Non-Steroidal Androgen Receptor Modulators, Preparation Process, Pharmaceutical Composition and Use Thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES (CN) | 2008-11-27 | — | — | US | disclosed |
| EP-1889829-A1 | NONSTEROIC ANDROGEN ACCEPTOR REGULATORS, PREPARATION PROCESS, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2008-02-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293808-A1 | Non-Steroidal Androgen Receptor Modulators, Preparation Process, Pharmaceutical Composition and Use Thereof | AR, NR5A1, CYP17A1 | MAPT 3155/4885MEN1 1215/4885KMT2A 4098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.