Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1277564 | 0.90 | SIGMAR1 (0.32) | — | |
| SCHEMBL27787894 | 0.88 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL27787910 | 0.88 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL1277889 | 0.87 | PDE4B (0.33) | ALDH1A1 | |
| SCHEMBL28787660 | 0.85 | VCP (0.36) | ALDH1A1 | |
| SCHEMBL1278123 | 0.83 | — | — | |
| SCHEMBL3020281 | 0.83 | SYK (0.33) | — | |
| SCHEMBL1278045 | 0.82 | — | — | |
| SCHEMBL1277949 | 0.82 | HTR2B (0.30) | — | |
| SCHEMBL1278089 | 0.81 | GABRA1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101801965-B | Indole compounds as inhibitors of cellular necrosis | LG LIFE SCIENCES LTD | 2014-07-30 | — | — | CN | claimed |
| CN-101801965-A | Indole compounds as inhibitors of cellular necrosis | LG LIFE SCIENCES LTD | 2010-08-11 | — | — | CN | claimed |
| CN-101801965-B | Indole compounds as inhibitors of cellular necrosis | LG LIFE SCIENCES LTD | 2014-07-30 | — | — | CN | disclosed |