Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 1/20 | 0.37 |
| ▸ | NPY4R | P50391 | 9/20 | 0.36 |
| ▸ | NPY1R | P25929 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 3/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | GNPAT | O15228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL117226 | 0.92 | NPY4R (0.41) | C3AR1NPY4RNPY1RMEN1KMT2A | |
| SCHEMBL14831956 | 0.86 | FOLH1 (0.38) | C3AR1NPY4RNPY1RMEN1KMT2A | |
| SCHEMBL27917943 | 0.84 | MEN1 (0.43) | C3AR1NPY4RNPY1RMEN1KMT2A | |
| SCHEMBL27917941 | 0.84 | MEN1 (0.43) | C3AR1NPY4RNPY1RMEN1KMT2A | |
| SCHEMBL27043232 | 0.83 | GNPAT (0.46) | C3AR1NPY4RNPY1RMEN1KMT2A | |
| SCHEMBL7196910 | 0.83 | GNPAT (0.46) | C3AR1NPY4RNPY1RMEN1KMT2A | |
| SCHEMBL408774 | 0.83 | GNPAT (0.46) | C3AR1NPY4RNPY1RMEN1KMT2A | |
| SCHEMBL12292041 | 0.83 | C3AR1 (0.41) | C3AR1NPY4RNPY1RMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3700024 | 0.82 | NPY4R (0.36) | NPY4RNPY1RKMT2AALOX15NPY2R | |
| Hydrochloric Acid SCHEMBL18222331 | 0.82 | GNPAT (0.45) | C3AR1NPY4RNPY1RMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102123723-B | Glucagon/GLP-1 receptor co-agonists | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORP. (US) | 2016-05-25 | — | — | CN | disclosed |
| CN-103079587-B | Glucagon superfamily peptides exhibiting nuclear hormone receptor activity | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORP. (US) | 2016-05-11 | — | — | CN | disclosed |
| CN-102088989-B | Glucagon analogs with enhanced solubility and stability in physiological pH buffers | UNIV INDIANA RES & TECH CORP | 2014-11-26 | — | — | CN | disclosed |
| CN-104114183-A | CTP-based insulin analogs for treatment of diabetes | UNIV INDIANA RES & TECH CORP | 2014-10-22 | — | — | CN | disclosed |
| CN-103957927-A | Glucagon superfamily peptides exhibiting glucocorticoid receptor activity | UNIV INDIANA RES & TECH CORP | 2014-07-30 | — | — | CN | disclosed |
| CN-103857408-A | Glucagon/glp-1 receptor co-agonists | UNIV INDIANA RES & AMP | 2014-06-11 | — | — | CN | disclosed |
| CN-103641907-A | Glucagon/glp-1 receptor co-agonists | UNIV INDIANA RES & TECH CORP | 2014-03-19 | — | — | CN | disclosed |
| CN-103458920-A | Glucagon analogs exhibiting GIP receptor activity | UNIV INDIANA RES & TECH CORP | 2013-12-18 | — | — | CN | disclosed |
| CN-103179979-A | Amide-based glucagon superfamily peptide prodrugs | UNIV INDIANA RES & TECH CORP | 2013-06-26 | — | — | CN | disclosed |
| CN-103179976-A | Glucagon superfamily peptides exhibiting g protein-coupled receptor activity | MARCADIA BIOTECH INC | 2013-06-26 | — | — | CN | disclosed |
| CN-103079587-A | Glucagon superfamily peptides exhibiting nuclear hormone receptor activity | UNIV INDIANA RES & TECH CORP | 2013-05-01 | — | — | CN | disclosed |
| CN-103068842-A | Single chain insulin agonists exhibiting high activity at the insulin receptor | UNIV INDIANA RES & TECH CORP | 2013-04-24 | — | — | CN | disclosed |
| CN-102834108-A | Glucagon antagonist-GIP agonist conjugates and compositions for treating metabolic disorders and obesity | UNIV INDIANA RES & TECH CORP | 2012-12-19 | — | — | CN | disclosed |
| CN-102459325-A | Gastrostatin receptor activated glucagon compounds | UNIV INDIANA RES & TECH CORP | 2012-05-16 | — | — | CN | disclosed |
| CN-102448482-A | Parathyroid hormone peptides and parathyroid hormone-related protein peptides and methods of use | VAN ANDEL RES INST | 2012-05-09 | — | — | CN | disclosed |
| CN-102325539-A | Amide based glucagon superfamily peptide prodrugs | UNIV INDIANA RES & TECH CORP | 2012-01-18 | — | — | CN | disclosed |
| CN-102123723-A | Glucagon/GLP-1 receptor co-agonists | UNIV INDIANA RES & TECH CORP | 2011-07-13 | — | — | CN | disclosed |
| CN-102105159-A | GIP-based mixed agonists for the treatment of metabolic disorders and obesity | UNIV INDIANA RES & TECH CORP | 2011-06-22 | — | — | CN | disclosed |
| CN-102088989-A | Glucagon analogs with enhanced solubility and stability in physiological pH buffers | UNIV INDIANA RES & TECH CORP | 2011-06-08 | — | — | CN | disclosed |