Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 9/20 | 0.41 |
| ▸ | NPY1R | P25929 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.34 |
| ▸ | Q9HBH1 | 1/20 | 0.34 | |
| ▸ | TGM2 | P21980 | 2/20 | 0.33 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 3/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27810936 | 0.92 | C3AR1 (0.37) | NPY4RNPY1RMEN1GAAKMT2A | |
| Trifluoroacetic Acid SCHEMBL29816943 | 0.83 | NPY4R (0.43) | NPY4RNPY1RC3AR1FOLH1 | |
| Trifluoroacetic Acid SCHEMBL117153 | 0.81 | NPY4R (0.37) | NPY4RNPY1RS1PR1S1PR3S1PR2 | |
| SCHEMBL27917943 | 0.80 | MEN1 (0.43) | NPY4RNPY1RMEN1GAAKMT2A | |
| SCHEMBL27917941 | 0.80 | MEN1 (0.43) | NPY4RNPY1RMEN1GAAKMT2A | |
| SCHEMBL14831956 | 0.79 | FOLH1 (0.38) | NPY4RNPY1RMEN1GAAKMT2A | |
| SCHEMBL12292041 | 0.79 | C3AR1 (0.41) | NPY4RNPY1RMEN1GAAKMT2A | |
| Trifluoroacetic Acid SCHEMBL7438898 | 0.79 | NPY4R (0.45) | NPY4RNPY1RC3AR1NPY2RNPY5R | |
| Trifluoroacetic Acid SCHEMBL7445678 | 0.79 | NPY4R (0.49) | NPY4RNPY1RC3AR1NPY2RNPY5R | |
| Trifluoroacetic Acid SCHEMBL7442422 | 0.78 | NPY4R (0.42) | NPY4RNPY1RMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9387185-B2 | N-ω-hydroxy-L-arginine derivatives for the treatment of diseases | CHRISTIAN-ALBRECHTS-UNIVERSITÄT ZU KIEL (DE) | 2016-07-12 | — | — | US | disclosed |
| US-20120123111-A1 | Nª -Hydroxy-L-Arginine Derivatives for the Treatment of Diseases | CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL (DE) | 2012-05-17 | — | — | US | disclosed |
| EP-2424515-A1 | N OMEGA-HYDROXY-L-ARGININE DERIVATIVES FOR THE TREATMENT OF DISEASES | Christian-Albrechts-Universität zu Kiel (DE) | 2012-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120123111-A1 | Nª -Hydroxy-L-Arginine Derivatives for the Treatment of Diseases | ARG2, ARG1, NOS2 | NPY4R 1403/4885NPY1R 1074/4885MEN1 2465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.