Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | MAP2K4 | P45985 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | MAPK6 | Q16659 | 3/20 | 0.43 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.43 |
| ▸ | KIF11 | P52732 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPKAPK3 | Q16644 | 2/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | SGK1 | O00141 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1513093 | 0.85 | TRPA1 (0.55) | GSK3BMAP2K4MAPK1MAPK6MAPKAPK5 | |
| SCHEMBL30586177 | 0.85 | TRPA1 (0.55) | GSK3BMAP2K4MAPK1MAPK6MAPKAPK5 | |
| Tert-Butyl Formate SCHEMBL27831787 | 0.78 | CYP1A2 (0.41) | GSK3BMAP2K4 | |
| SCHEMBL14738709 | 0.76 | KIF11 (0.46) | GSK3BMAP2K4MAPK1MAPK6MAPKAPK5 | |
| SCHEMBL26124043 | 0.73 | PRKAA1 (0.41) | GSK3BMAP2K4MAPK1MAPK6MAPKAPK5 | |
| SCHEMBL14631813 | 0.73 | MAP2K4 (0.56) | GSK3BMAP2K4MAPK1MAPK6MAPKAPK5 | |
| Tert-Butyl Formate SCHEMBL27831769 | 0.72 | KDR (0.34) | KIF11 | |
| SCHEMBL26980085 | 0.72 | TRPA1 (0.51) | GSK3BMAP2K4MAPK1MAPK6MAPKAPK5 | |
| SCHEMBL29644237 | 0.72 | TRPA1 (0.51) | GSK3BMAP2K4MAPK1MAPK6MAPKAPK5 | |
| Tert-Butyl Formate SCHEMBL27819460 | 0.72 | PDPK1 (0.41) | GSK3BMAP2K4MAPK1MAPK6MAPKAPK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102089302-A | Nitrogenated bicyclic heterocyclic compound | ASAHI KASEI PHARMA CORP | 2011-06-08 | — | — | CN | disclosed |