Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24928816 | 0.90 | HDAC8 (0.40) | HDAC8HDAC6HDAC1L3MBTL1DRD2 | |
| SCHEMBL26999889 | 0.83 | L3MBTL1 (0.54) | L3MBTL1DRD2ABCG2ALDH1A1 | |
| SCHEMBL19360211 | 0.83 | L3MBTL1 (0.39) | HDAC8HDAC6HDAC1L3MBTL1DRD2 | |
| SCHEMBL4061867 | 0.82 | HDAC8 (0.39) | HDAC8HDAC6HDAC1L3MBTL1DRD2 | |
| SCHEMBL12706905 | 0.81 | OPRD1 (0.47) | HDAC8HDAC6HDAC1L3MBTL1DRD2 | |
| SCHEMBL6922946 | 0.81 | SMN1; SMN2 (0.45) | HDAC8HDAC6HDAC1L3MBTL1ALDH1A1 | |
| SCHEMBL863635 | 0.81 | SMN1; SMN2 (0.45) | HDAC8HDAC6HDAC1L3MBTL1ALDH1A1 | |
| SCHEMBL4088779 | 0.80 | CHRNB2 (0.44) | — | |
| SCHEMBL4088784 | 0.80 | CHRNB2 (0.44) | — | |
| SCHEMBL28008568 | 0.79 | CHRM3 (0.45) | HDAC8HDAC6HDAC1L3MBTL1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101815713-A | Polycyclic compounds | EISAI R&D MAN CO LTD | 2010-08-25 | — | — | CN | disclosed |