Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.56 |
| ▸ | UGCG | Q16739 | 12/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.52 |
| ▸ | PPOX | P50336 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2783088 | 0.91 | ALK (0.49) | MRGPRX4UGCGCYP3A4MEN1TTR | |
| SCHEMBL2782226 | 0.85 | TAS2R14 (0.48) | MRGPRX4UGCGCYP3A4MEN1TTR | |
| SCHEMBL2783223 | 0.84 | CCR2 (0.47) | KMT2A | |
| SCHEMBL2336929 | 0.83 | MRGPRX4 (0.54) | MRGPRX4UGCGTTRTDP1 | |
| SCHEMBL2779685 | 0.82 | MRGPRX4 (0.47) | MRGPRX4TDP1 | |
| SCHEMBL2779965 | 0.81 | ROCK2 (0.46) | MEN1KMT2ATDP1 | |
| SCHEMBL10924171 | 0.81 | CCR1 (0.60) | MRGPRX4MEN1TTRPPOXKMT2A | |
| SCHEMBL2785360 | 0.80 | TDP1 (0.54) | CYP3A4MEN1TTRKMT2ATDP1 | |
| SCHEMBL2782132 | 0.80 | MAPK8 (0.53) | MRGPRX4MEN1KMT2ATDP1 | |
| SCHEMBL2332795 | 0.79 | TP53 (0.52) | MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114380740-A | Synthesis method of polysubstituted pyridine-2-oxygen ether compound | 江阴苏利化学股份有限公司 | 2022-04-22 | — | — | CN | disclosed |
| WO-2010091104-A1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | EXELIXIS, INC. (US) | 2010-08-12 | — | — | WO | disclosed |
| WO-2010091104-A1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | EXELIXIS, INC. (US) | 2010-08-12 | — | — | WO | disclosed |