Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.53 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MIF | P14174 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6215399 | 0.88 | NPC1 (0.60) | RAB9AALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL8143171 | 0.86 | KDM4E (0.64) | RAB9AALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL255828 | 0.80 | ALDH1A1 (0.64) | RAB9AALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL8145039 | 0.80 | RAB9A (0.77) | RAB9AALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL27821590 | 0.79 | MEN1 (0.57) | RAB9AALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL27911826 | 0.77 | ALDH1A1 (0.58) | RAB9AALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL8136410 | 0.77 | ALDH1A1 (0.55) | RAB9AALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL31030144 | 0.77 | ALDH1A1 (0.54) | RAB9AALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL13499907 | 0.76 | KMT2A (0.61) | RAB9AALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL27911817 | 0.75 | ALDH1A1 (0.56) | RAB9AALDH1A1NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101948466-B | Asymmetric heterocyclic ring substituent urea compound and preparation method and application thereof | UNIV NANKAI | 2014-04-16 | — | — | CN | disclosed |
| CN-101948466-A | Asymmetric heterocyclic ring substituent urea compound and preparation method and application thereof | UNIV NANKAI | 2011-01-19 | — | — | CN | disclosed |