Glycerin

Glycerin

SCHEMBL2782166

O=C(O)OCC(Cl)(Cl)Cl.OCC(O)CO

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
LMNA P02545 2/20 0.38
OR51E2 Q9H255 1/20 0.31
TP53 P04637 1/20 0.31
TSHR P16473 1/20 0.31
HTT P42858 1/20 0.30
KDM4E B2RXH2 1/20 0.30
DUSP3 P51452 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL41347 0.84
Hydrochloric Acid SCHEMBL4386155 0.82 ALDH1A1 (0.33) ALDH1A1TP53TSHR
SCHEMBL2782170 0.76 KDM4E (0.39) LMNAKDM4EDUSP3MEN1KMT2A
Glycerin SCHEMBL7727938 0.75 LMNA (0.47) ALDH1A1LMNAOR51E2KDM4EDUSP3
Trichloroacetic Acid SCHEMBL10360048 0.74 ALDH1A1 (0.59) ALDH1A1LMNAOR51E2TP53TSHR
Bicarbonate SCHEMBL9405407 0.73 USP2 (0.36) ALDH1A1LMNAOR51E2KDM4EDUSP3
Glycerin SCHEMBL16774835 0.71 ALDH1A1 (0.43) ALDH1A1LMNAOR51E2KDM4EDUSP3
SCHEMBL44489 0.70
SCHEMBL6471028 0.70 HTT (0.58) ALDH1A1HTT
SCHEMBL2905861 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100330033-A1 Protein-carrier conjugates WU NIAN 2010-12-30 US disclosed
WO-2010120365-A2 PROTEIN-CARRIER CONJUGATES WU NIAN (US) 2010-10-21 WO disclosed
WO-1992013447-A1 TEMPLATE POLYMERIZATION USING METAL CHELATES AND FLUID IMPRINT MATRICES CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1992-08-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100330033-A1 Protein-carrier conjugates CHLSN, PCTP, CETP ALDH1A1 3570/4885LMNA 3621/4885OR51E2 3004/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.