SCHEMBL41347

SCHEMBL41347

O=C(O)OCC(Cl)(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4386155 0.97 ALDH1A1 (0.33)
Glycerin SCHEMBL2782166 0.84 ALDH1A1 (0.38)
Succinimide SCHEMBL11594035 0.79 CRBN (0.41)
SCHEMBL9230930 0.79 ALDH1A1 (0.34)
Clorethate SCHEMBL41346 0.79 CHRM2 (0.39)
SCHEMBL1408772 0.78 ALDH1A1 (0.37)
SCHEMBL9230926 0.78 ALDH1A1 (0.32)
SCHEMBL28182083 0.77 ALDH1A1 (0.34)
SCHEMBL3023 0.77
SCHEMBL969230 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2946 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035402-A1 C10-ALKYLENE SUBSTITUTED 13-MEMBERED MACROLIDES AND USES THEREOF ZIKANI THERAPEUTICS INC (US) 2026-02-05 US claimed
US-12060334-B2 3-substituted phenazine derivatives as antimicrobial agents UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-08-13 US claimed
US-11834470-B2 4-thioribose NAD analogues and methods of synthesizing and using the same UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2023-12-05 US claimed
US-11634449-B2 Macrolides and methods of their preparation and use PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-04-25 US claimed
EP-3649135-B1 SYNTHESIS OF HALICHONDRINS HARVARD COLLEGE (US) 2022-12-28 EP claimed
US-20220332747-A1 MACROLIDES AND METHODS OF THEIR PREPARATION AND USE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2022-10-20 US claimed
EP-3291676-B1 MITRAGYNINE ANALOGS AND USES THEREOF MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2022-08-17 EP claimed
US-20220227803-A1 4-THIORIBOSE NAD ANALOGUES AND METHODS OF SYNTHESIZING AND USING THE SAME NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-07-21 US claimed
US-11241435-B2 Uses of salt-inducible kinase (SIK) inhibitors for treating osteoporosis THE GENERAL HOSPITAL CORPORATION (US) 2022-02-08 US claimed
WO-2022016195-A1 PROCESSES FOR THE PREPARATION OF ARGINASE INHIBITORS AND THEIR SYNTHETIC INTERMEDIATES INCYTE CORPORATION (US) 2022-01-20 WO claimed
WO-1997034924-A1 PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF LHRH ANTAGONISTS ABBOTT LABORATORIES (US) 1997-09-25 WO claimed
EP-0773938-A1 SEMI-SYNTHETIC TAXANES WITH ANTI-TUMOURAL ACTIVITY INDENA S.p.A. (IT) 1997-05-21 EP claimed
WO-1996003394-A1 SEMI-SYNTHETIC TAXANES WITH ANTI-TUMOURAL ACTIVITY INDENA S.P.A. (IT) 1996-02-08 WO claimed
US-5446134-A Reacting bis(fluorosulfonyl)methane salt with cyanogen halide or pseudohalide CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1995-08-29 US claimed
US-5401858-A Preparation of quinic acid derivatives NESTEC S.A. (CH) 1995-03-28 US claimed
US-5395950-A Production of quinic acid derivatives NESTEC S.A. (CH) 1995-03-07 US claimed
EP-0581980-A1 3- and/or 4-substituted derivatives of quinic acid and process to prepare 3- and/or 4-substituted derivatives of quinic acid SOCIETE DES PRODUITS NESTLE S.A. (CH) 1994-02-09 EP claimed
EP-0581979-A1 Quinic acid derivatives and process to prepare quinic acid derivatives SOCIETE DES PRODUITS NESTLE S.A. (CH) 1994-02-09 EP claimed
US-4415567-A A 7B-CHROMONE-3-CARBOXAMIDO-2-/4-HYDROXY PHENYL/ACETAMIDO-2-CEPHEM DERIVATIVE EISAI CO., LTD. (JP) 1983-11-15 US claimed
US-4344944-A 7-α-methoxycephalosporin derivatives, and antibacterial drugs onctaining the same EISAI CO., LTD. (JP) 1982-08-17 US claimed