Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 6/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1971791 | 0.71 | IMPDH2 (0.47) | PRMT5WDR77ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL27831895 | 0.68 | IGLV6-57 (0.41) | ALDH1A1GAAKDM4EMEN1KMT2A | |
| SCHEMBL16518824 | 0.65 | KDM4E (0.41) | ALDH1A1GAAL3MBTL1NPC1RAB9A | |
| SCHEMBL15536272 | 0.62 | MCL1 (0.52) | NPC1 | |
| SCHEMBL15334010 | 0.62 | TRPA1 (0.56) | ALDH1A1KDM4ECYP1A2HPGD | |
| SCHEMBL1971648 | 0.62 | KDM4E (0.46) | ALDH1A1KDM4ECYP1A2HPGDKMT2A | |
| SCHEMBL3821760 | 0.62 | ALDH1A1 (0.41) | ALDH1A1GAAGLARAB9AKDM4E | |
| SCHEMBL27811660 | 0.61 | CNR1 (0.37) | ALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL16456343 | 0.59 | TNKS (0.41) | ALDH1A1GAAL3MBTL1NPC1MAPK1 | |
| SCHEMBL10692239 | 0.59 | DAO (0.41) | ALDH1A1GAAL3MBTL1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102164909-A | Pyrine or pyrazine derivatives for treating HCV | HOFFMANN LA ROCHE | 2011-08-24 | — | — | CN | claimed |