Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1479710 | 0.91 | — | — | |
| SCHEMBL1479711 | 0.91 | — | — | |
| Acetic Acid SCHEMBL27827142 | 0.76 | NOS2 (0.30) | — | |
| SCHEMBL4449114 | 0.71 | — | — | |
| SCHEMBL4241571 | 0.71 | — | — | |
| SCHEMBL23710692 | 0.71 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL10930795 | 0.70 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL2083857 | 0.70 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL15520994 | 0.69 | HSD17B10 (0.42) | ALDH1A1 | |
| SCHEMBL6674331 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130087072-A1 | Reversibly Switchable Surfactants and Methods of Use Thereof | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2013-04-11 | — | — | US | disclosed |
| US-8283385-B2 | Emulsion polymerization; oil industry | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2012-10-09 | — | — | US | disclosed |
| US-20080197084-A1 | Reversibly switchable surfactants and methods of use thereof | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080197084-A1 | Reversibly switchable surfactants and methods of use thereof | SGMS1, SGMS2, HDHD5 | ALDH1A1 3854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.