Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 2/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27686537 | 1.00 | HDAC3 (0.32) | HDAC3AKT1CES2CES1KMT2A | |
| SCHEMBL9303552 | 0.76 | CES2 (0.46) | HDAC3CES2CES1PTGS2 | |
| SCHEMBL9303827 | 0.75 | ATM (0.43) | HDAC3CES2CES1KMT2APTGS2 | |
| SCHEMBL4389892 | 0.71 | AKT1 (0.34) | AKT1 | |
| SCHEMBL27564615 | 0.71 | HDAC1 (0.37) | CES1KMT2A | |
| SCHEMBL16411369 | 0.69 | CES1 (0.41) | CES2CES1KMT2A | |
| SCHEMBL2380219 | 0.69 | MAOA (0.44) | HDAC3AKT1KMT2A | |
| SCHEMBL10020655 | 0.69 | MAPT (0.52) | HDAC3AKT1CES1KMT2A | |
| SCHEMBL10881094 | 0.69 | MAPT (0.52) | HDAC3AKT1CES1KMT2A | |
| SCHEMBL3031432 | 0.69 | MAOA (0.44) | HDAC3AKT1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1997614-B | Synthesis of 6-aryl-6-alkyl fulvenes, 6-aryl-6-alkenyl fulvenes, and related compounds | Chevron Phillips Chemical Co.,L.P. (US) | 2012-02-01 | — | — | CN | disclosed |