SCHEMBL9303827

SCHEMBL9303827

CCC(=C1C=CC=C1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.43
CES1 P23141 4/20 0.42
CES2 O00748 3/20 0.42
HDAC6 Q9UBN7 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
HPGD P15428 2/20 0.38
ALDH1A1 P00352 1/20 0.38
RAB9A P51151 1/20 0.38
ELANE P08246 1/20 0.38
ESR1 P03372 2/20 0.37
CYP19A1 P11511 1/20 0.37
ESR2 Q92731 1/20 0.37
HDAC3 O15379 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC10 Q969S8 1/20 0.37
HDAC11 Q96DB2 1/20 0.37
HDAC8 Q9BY41 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9303552 0.83 CES2 (0.46) ATMCES1CES2HDAC6HPGD
SCHEMBL11319329 0.79 HTR7 (0.39) CES1CES2HPGDALDH1A1RAB9A
SCHEMBL27564615 0.78 HDAC1 (0.37) CES1TDP1HPGDHDAC1HDAC2
SCHEMBL16411369 0.77 CES1 (0.41) CES1CES2HDAC6ALDH1A1HDAC8
SCHEMBL27827293 0.75 HDAC3 (0.32) CES1CES2HDAC3PTGS2KMT2A
SCHEMBL27686537 0.75 HDAC3 (0.32) CES1CES2HDAC3PTGS2KMT2A
SCHEMBL647841 0.74 TDP1 (0.40) ATMCES1CES2HDAC6TDP1
SCHEMBL20521982 0.71 TDP1 (0.53) HDAC6TDP1RAB9AHDAC3HDAC4
SCHEMBL4389892 0.71 AKT1 (0.34) HPGDALDH1A1MAPTLMNAMAPK1
SCHEMBL6890595 0.70 CES2 (0.41) ATMCES1CES2ALDH1A1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5349100-A Chiral metallocene compounds and preparation thereof by creation of a chiral center by enantioselective hydride transfer EXXON CHEMICAL PATENTS INC. (US) 1994-09-20 US claimed
WO-1992012112-A1 CHIRAL METALLOCENE COMPOUNDS AND PREPARATION THEREOF BY CREATION OF A CHIRAL CENTER BY ENANTIOSELECTIVE HYDRIDE TRANSFER EXXON CHEMICAL PATENTS INC. (US) 1992-07-23 WO claimed
US-5349100-A Chiral metallocene compounds and preparation thereof by creation of a chiral center by enantioselective hydride transfer EXXON CHEMICAL PATENTS INC. (US) 1994-09-20 US disclosed
WO-1992012112-A1 CHIRAL METALLOCENE COMPOUNDS AND PREPARATION THEREOF BY CREATION OF A CHIRAL CENTER BY ENANTIOSELECTIVE HYDRIDE TRANSFER EXXON CHEMICAL PATENTS INC. (US) 1992-07-23 WO disclosed
US-4264336-A FOR IMPROVING THE OCTANE QUALITY OF UNLEADED GASOLINE PHILLIPS PETROLEUM COMPANY (US) 1981-04-28 US disclosed