SCHEMBL4389892

SCHEMBL4389892

C=CCCC(=C1C=CC=C1)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 1/20 0.34
ALDH1A1 P00352 3/20 0.33
LMNA P02545 2/20 0.33
HPGD P15428 1/20 0.33
ACHE P22303 1/20 0.33
POLB P06746 2/20 0.33
USP2 O75604 1/20 0.33
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
IDH1 O75874 1/20 0.32
HRH1 P35367 1/20 0.31
OGG1 O15527 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4387095 0.90 L3MBTL1 (0.34) AKT1ALDH1A1LMNAHPGDACHE
SCHEMBL20521131 0.88 MAPT (0.38) AKT1ALDH1A1LMNAHPGDPOLB
SCHEMBL4758846 0.81 SMN1; SMN2 (0.44) ALDH1A1HPGDMAPTMAPK1
SCHEMBL27737740 0.72 AKT1 (0.41) AKT1ALDH1A1LMNAHPGDPOLB
SCHEMBL27686537 0.71 HDAC3 (0.32) AKT1
SCHEMBL27827293 0.71 HDAC3 (0.32) AKT1
SCHEMBL20521982 0.71 TDP1 (0.53) MAPTMAPK1
SCHEMBL9303827 0.71 ATM (0.43) ALDH1A1LMNAHPGDMAPTMAPK1
SCHEMBL1678464 0.71 MAOA (0.45) AKT1ALDH1A1LMNAHPGDPOLB
SCHEMBL27564615 0.71 HDAC1 (0.37) LMNAHPGDPOLBMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121574291-A Borate activated metallocene catalysts 博里利斯股份公司 2026-02-27 CN disclosed
CN-110494458-B Alumoxane-activated metallocene catalysts 博里利斯股份公司 2023-08-15 CN disclosed
EP-3601385-B1 BORATE-ACTIVATED METALLOCENE CATALYSTS BOREALIS AG (AT) 2023-05-03 EP disclosed
EP-3601384-B1 ALUMINOXANE-ACTIVATED METALLOCENE CATALYSTS BOREALIS AG (AT) 2023-05-03 EP disclosed
US-11560440-B2 Aluminoxane-activated metallocene catalysts BOREALIS AG (AT) 2023-01-24 US disclosed
US-11192963-B2 Borate-activated metallocene catalysts BOREALIS AG (AT) 2021-12-07 US disclosed
US-11192963-B2 Borate-activated metallocene catalysts BOREALIS AG (AT) 2021-12-07 US disclosed
US-20210108006-A1 BORATE-ACTIVATED METALLOCENE CATALYSTS BOREALIS AG (AT) 2021-04-15 US disclosed
US-20210108006-A1 BORATE-ACTIVATED METALLOCENE CATALYSTS BOREALIS AG (AT) 2021-04-15 US disclosed
US-20210095057-A1 ALUMINOXANE-ACTIVATED METALLOCENE CATALYSTS BOREALIS AG (AT) 2021-04-01 US disclosed
EP-1917281-A1 POLYMERIZATION CATALYSTS AND PROCESS FOR PRODUCING BIMODAL POLYMERS IN A SINGLE REACTOR Chevron Phillips Chemical Company LP (US) 2008-05-07 EP disclosed
US-7312283-B2 Polymerization catalysts and process for producing bimodal polymers in a single reactor CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2007-12-25 US disclosed
CN-1997614-A Synthesis of 6-aryl-6-alkyl fulvenes, 6-aryl-6-alkenyl fulvenes, and related compounds CHEVRON PHILLIPS CHEMICAL CO (US) 2007-07-11 CN disclosed
WO-2007055978-A1 MULTIMODAL POLYETHYLENE COMPOSITIONS AND PIPES MADE FROM THE SAME MULTIMODAL POLYETHYLENE COMPOSITION CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2007-05-18 WO disclosed
EP-1778606-A1 SYNTHESIS OF 6-ARYL-6-ALKYL FULVENES, 6-ARYL-6-ALKENYL FULVENES, AND RELATED COMPOUNDS Chevron Phillips Chemical Company (US) 2007-05-02 EP disclosed
WO-2007024773-A1 POLYMERIZATION CATALYSTS AND PROCESS FOR PRODUCING BIMODAL POLYMERS IN A SINGLE REACTOR CHEVRON PHILLIPS CHEMICAL CO LP (US) 2007-03-01 WO disclosed
US-20070043176-A1 Polymerization catalysts and process for producing bimodal polymers in a single reactor CHEVRON PHILLIPS CHEMICAL COMPANY, L.P. 2007-02-22 US disclosed
US-20070043182-A1 Multimodal polyethylene compositions and pipe made from same CHEVRON PHILLIPS CHEMICAL COMPANY LP 2007-02-22 US disclosed
WO-2006004669-A1 IMPROVED SYNTHESIS OF 6-ARYL-6-ALKYL FULVENES, 6-ARYL-6-ALKENYL FULVENES, AND RELATED COMPOUNDS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2006-01-12 WO disclosed
US-20050288524-A1 Synthesis of 6-aryl-6-alkyl fulvenes, 6-aryl-6-alkenyl fulvenes, and related compounds CHEVRON PHILLIPS CHEMICAL COMPANY 2005-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050288524-A1 Synthesis of 6-aryl-6-alkyl fulvenes, 6-aryl-6-alkenyl fulvenes, and related compounds ANXA6, ARSA, CYP2A6 AKT1 3978/4885ALDH1A1 2633/4885LMNA 1094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.