Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.40 |
| ▸ | GCGR | P47871 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3637569 | 0.80 | NPC1 (0.46) | MAPTLMNAMAPK14GCGRNOTUM | |
| SCHEMBL27818185 | 0.77 | HDAC4 (0.35) | CYP11B2CYP3A4CYP17A1CYP11B1 | |
| SCHEMBL19908987 | 0.77 | SQOR (0.43) | MAPTLMNAMAPK14GCGRAKR1C3 | |
| SCHEMBL1685615 | 0.76 | ALOX5AP (0.47) | MAPTLMNAAKR1C3AKR1C2PDE3B | |
| SCHEMBL6219693 | 0.76 | ALOX5AP (0.39) | AKR1C3AKR1C2PDE3BPDE3ACYP11B2 | |
| SCHEMBL27475857 | 0.75 | CYP11B1 (0.55) | MAPTLMNAAKR1C3AKR1C2PDE3B | |
| SCHEMBL16242320 | 0.75 | TGFBR1 (0.38) | PDE3BPDE3A | |
| SCHEMBL29131318 | 0.74 | ALOX5AP (0.46) | MAPTLMNAAKR1C3AKR1C2PDE3B | |
| SCHEMBL8015322 | 0.74 | NR4A2 (0.40) | LMNA | |
| SCHEMBL5716618 | 0.74 | CTSL (0.44) | PDE3BPDE3ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102307887-A | Light-emitting material for use as host dopant in emissive layer for OLEDs | SOLVAY | 2012-01-04 | — | — | CN | disclosed |