Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13263254 | 0.84 | WDR5 (0.47) | BACE1WDR5MAPTCNR2 | |
| SCHEMBL2649506 | 0.82 | NPC1 (0.58) | NPC1RAB9APKMKMT2ALMNA | |
| SCHEMBL30418017 | 0.82 | NPC1 (0.58) | NPC1RAB9APKMKMT2ALMNA | |
| SCHEMBL27831776 | 0.80 | MAPT (0.43) | LMNAMAPTNOTUMMAPK14GCGR | |
| Hydrochloric Acid SCHEMBL9010527 | 0.80 | WDR5 (0.40) | NPC1RAB9APKMKMT2ALMNA | |
| SCHEMBL200742 | 0.79 | ALDH1A1 (0.42) | NPC1RAB9APKMKMT2ALMNA | |
| SCHEMBL1423922 | 0.79 | NPC1 (0.46) | NPC1RAB9APKMKMT2ALMNA | |
| Methane SCHEMBL28995944 | 0.77 | ALDH1A1 (0.41) | NPC1RAB9APKMKMT2ALMNA | |
| SCHEMBL27346716 | 0.77 | ALDH1A1 (0.41) | NPC1RAB9APKMKMT2ALMNA | |
| SCHEMBL18253157 | 0.77 | ADRA1A (0.43) | WDR5MAPTCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107353308-B | Two thiophene phenol ethylene complex of iridium of phosphorescence conversion behavior and preparation method thereof with soda acid induction | 南京大学 | 2019-10-18 | — | — | CN | claimed |
| CN-103280535-A | White light organic electroluminescence device | GUANGZHOU SKYWORTH FLAT DISPLAY TECHNOLOGY CO LTD | 2013-09-04 | — | — | CN | claimed |
| CN-107353308-B | Two thiophene phenol ethylene complex of iridium of phosphorescence conversion behavior and preparation method thereof with soda acid induction | 南京大学 | 2019-10-18 | — | — | CN | disclosed |
| CN-107353308-B | Two thiophene phenol ethylene complex of iridium of phosphorescence conversion behavior and preparation method thereof with soda acid induction | 南京大学 | 2019-10-18 | — | — | CN | disclosed |
| CN-107353308-A | Two thiophene phenol ethene complex of iridium of phosphorescence conversion behavior with soda acid induction and preparation method thereof | 南京大学 | 2017-11-17 | — | — | CN | disclosed |
| CN-102844313-B | Compositions and methods for enhancing proteasome activity | 哈佛大学校长及研究员协会 | 2016-10-05 | — | — | CN | disclosed |
| CN-103119047-B | Tricyclic proteasome activity enhancing compounds | 哈佛大学校长及研究员协会 | 2016-06-15 | — | — | CN | disclosed |
| CN-103280535-A | White light organic electroluminescence device | GUANGZHOU SKYWORTH FLAT DISPLAY TECHNOLOGY CO LTD | 2013-09-04 | — | — | CN | disclosed |
| EP-2190945-A1 | ORGANIC RADIATION-EMITTING COMPONENT | OSRAM Opto Semiconductors GmbH (DE) | 2010-06-02 | — | — | EP | disclosed |
| EP-2167608-A2 | PHOSPHORESCENT METAL COMPLEX COMPOUND RADIATION EMITTING COMPONENT COMPRISING A PHOSPHORESCENT METAL COMPLEX COMPOUND AND METHOD FOR PRODUCTION OF A PHOSPHORESCENT METAL COMPLEX COMPOUND | OSRAM Opto Semiconductors GmbH (DE) | 2010-03-31 | — | — | EP | disclosed |
| WO-2009039845-A1 | ORGANIC RADIATION-EMITTING COMPONENT | OSRAM OPTO SEMICONDUCTORS GMBH (DE) | 2009-04-02 | — | — | WO | disclosed |
| WO-2008141637-A2 | PHOSPHORESCENT METAL COMPLEX COMPOUND RADIATION EMITTING COMPONENT COMPRISING A PHOSPHORESCENT METAL COMPLEX COMPOUND AND METHOD FOR PRODUCTION OF A PHOSPHORESCENT METAL COMPLEX COMPOUND | OSRAM OPTO SEMICONDUCTORS GMBH (DE) | 2008-11-27 | — | — | WO | disclosed |