Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | TMPRSS4 | Q9NRS4 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 3/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10437219 | 0.77 | TMPRSS4 (0.36) | HTTALDH1A1CSNK2A1TMPRSS4ESR1 | |
| SCHEMBL5733013 | 0.77 | CYP11B1 (0.35) | HTTNOTUMSMN1; SMN2LMNAKIF11 | |
| SCHEMBL25077559 | 0.74 | ESR2 (0.44) | HTTKDM4EALDH1A1GAACSNK2A1 | |
| SCHEMBL13199169 | 0.74 | AR (0.38) | GAANOTUMKIF11POLBTAS2R14 | |
| SCHEMBL31235049 | 0.72 | KIF11 (0.37) | CSNK2A1NOTUMTMPRSS4ESR1ESR2 | |
| SCHEMBL2878061 | 0.71 | NOTUM (0.38) | HTTNOTUMSMN1; SMN2LMNATAS2R14 | |
| SCHEMBL7524173 | 0.71 | KDM4E (0.39) | HTTKDM4EALDH1A1GAACSNK2A1 | |
| SCHEMBL6785116 | 0.71 | TRPA1 (0.37) | TMPRSS4KIF11TRPA1ATMAR | |
| SCHEMBL23226966 | 0.71 | TMPRSS4 (0.41) | CSNK2A1TMPRSS4KIF11TRPA1ATM | |
| SCHEMBL27511112 | 0.71 | APP (0.36) | HTTKDM4EALDH1A1GAACSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102093230-B | Type I forked biphenyl diamine and preparation method and application thereof | CHENGDU JINJIANG NEW HIGH MATERIAL CO LTD | 2013-06-12 | — | — | CN | disclosed |
| CN-102093230-A | Type I forked biphenyl diamine and preparation method and application thereof | CHENGDU JINJIANG NEW HIGH MATERIAL CO LTD | 2011-06-15 | — | — | CN | disclosed |