Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 3/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10437219 | 0.85 | TMPRSS4 (0.36) | TRPA1ATMTMPRSS4KIF11AR | |
| SCHEMBL23226966 | 0.75 | TMPRSS4 (0.41) | TRPA1ATMTMPRSS4KIF11AR | |
| SCHEMBL17274386 | 0.75 | NOTUM (0.35) | — | |
| SCHEMBL27624595 | 0.74 | TRPA1 (0.42) | TRPA1ATM | |
| SCHEMBL8621898 | 0.73 | TAS2R14 (0.44) | — | |
| SCHEMBL9367573 | 0.72 | KIF11 (0.33) | TMPRSS4KIF11HSD17B1HSD17B2 | |
| SCHEMBL27831995 | 0.71 | HTT (0.36) | TRPA1ATMTMPRSS4KIF11AR | |
| SCHEMBL28037507 | 0.71 | AR (0.51) | AR | |
| SCHEMBL11318062 | 0.70 | TRPA1 (0.44) | TRPA1ATMAR | |
| SCHEMBL8615552 | 0.70 | CFTR (0.45) | ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092754-A1 | Derivatives of 4-(trifluoromethyl)-phenol and 4-(trifluoromethylphenyl)-2-(tetrahydropyranyl) ether and method for producing the same | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092754-A1 | Derivatives of 4-(trifluoromethyl)-phenol and 4-(trifluoromethylphenyl)-2-(tetrahydropyranyl) ether and method for producing the same | EPX, CYP4X1, EPHX2 | TRPA1 3097/4885ATM 3726/4885TMPRSS4 2846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.