Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | STAT1 | P42224 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2477935 | 0.87 | NPC1 (0.57) | MEN1KMT2ALMNAMAPTNPC1 | |
| SCHEMBL27716616 | 0.83 | GAA (0.55) | MEN1KMT2ALMNAMAPTNPC1 | |
| SCHEMBL17373926 | 0.79 | MGLL (0.60) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL877775 | 0.76 | KMT2A (0.65) | MEN1KMT2ALMNAMAPTNPC1 | |
| SCHEMBL8701481 | 0.74 | KMT2A (0.62) | MEN1KMT2ALMNAMAPTNPC1 | |
| SCHEMBL6682458 | 0.74 | KMT2A (0.58) | MEN1KMT2ALMNAMAPTNPC1 | |
| SCHEMBL7401922 | 0.73 | MAPT (0.49) | MEN1KMT2ALMNAMAPTNPC1 | |
| SCHEMBL28406890 | 0.73 | MAPT (0.49) | MEN1KMT2ALMNAMAPTNPC1 | |
| SCHEMBL27668109 | 0.73 | GAA (0.55) | MEN1KMT2ALMNAMAPTNPC1 | |
| SCHEMBL28308932 | 0.72 | ALOX5 (0.51) | MEN1KMT2ALMNAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102224139-B | 4- (azacycloalkyl) benzene-1, 3-diol compounds as tyrosinase inhibitors, process for their preparation and their use in human medicine and cosmetics | GALDERMA RES & DEV | 2014-11-19 | — | — | CN | disclosed |
| CN-102224139-A | Novel 4- (azacycloalkyl) benzene-1, 3-diol compounds as tyrosinase inhibitors, process for their preparation and their use in human medicine and cosmetics | GALDERMA RES & DEV | 2011-10-19 | — | — | CN | disclosed |