Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | BCL9 | O00512 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.44 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9366960 | 0.83 | GAA (0.47) | MAPTSMN1; SMN2ALDH1A1GAAKDM4E | |
| SCHEMBL9519014 | 0.82 | RAB9A (0.49) | MAPTSMN1; SMN2ALDH1A1GAAKDM4E | |
| SCHEMBL6322393 | 0.81 | SMN1; SMN2 (0.64) | MAPTSMN1; SMN2ALDH1A1GAAKDM4E | |
| SCHEMBL20377184 | 0.81 | SMN1; SMN2 (0.64) | MAPTSMN1; SMN2ALDH1A1GAAKDM4E | |
| SCHEMBL12872528 | 0.81 | MAPT (0.57) | MAPTSMN1; SMN2ALDH1A1KDM4EKMT2A | |
| SCHEMBL26374 | 0.81 | GAA (0.65) | MAPTSMN1; SMN2ALDH1A1GAAKMT2A | |
| SCHEMBL3502988 | 0.80 | LMNA (0.60) | MAPTSMN1; SMN2ALDH1A1GAAKDM4E | |
| SCHEMBL7414455 | 0.80 | MEN1 (0.57) | MAPTSMN1; SMN2ALDH1A1GAAKDM4E | |
| Hydrochloric Acid SCHEMBL7895043 | 0.79 | GAA (0.62) | MAPTSMN1; SMN2ALDH1A1GAAKMT2A | |
| SCHEMBL450118 | 0.79 | CES2 (0.46) | SMN1; SMN2ALDH1A1GAAKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610431-A1 | HIV PROTEASE INHIBITORS CONTAINING GUANIDINE | SMITHKLINE BEECHAM CORPORATION (US) | 1994-08-17 | — | — | EP | disclosed |
| WO-1993009132-A1 | HIV PROTEASE INHIBITORS CONTAINING GUANIDINE | SMITHKLINE BEECHAM CORPORATION (US) | 1993-05-13 | — | — | WO | disclosed |