Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | HTR2B | P41595 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | HTR1B | P28222 | 6/20 | 0.38 |
| ▸ | HTR1D | P28221 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27833198 | 0.81 | HTR1A (0.72) | HTR1AHTR2AHTR2BLMNAADRA2B | |
| SCHEMBL13551485 | 0.80 | HTR1A (0.64) | HTR1AHTR2AHTR2BLMNAADRA2B | |
| SCHEMBL20648040 | 0.73 | MAPT (0.43) | HTR1AHTR2AHTR2BLMNAHTR1B | |
| SCHEMBL2788456 | 0.71 | LMNA (0.48) | HTR1AHTR2AHTR2BLMNAADRA2B | |
| SCHEMBL189974 | 0.70 | HTR1A (0.68) | HTR1AHTR2AHTR2BLMNAADRA2B | |
| SCHEMBL1847568 | 0.70 | HTR1A (0.74) | HTR1AHTR2AHTR2BLMNAADRA2B | |
| SCHEMBL2791148 | 0.70 | HTR1A (0.74) | HTR1AHTR2AHTR2BLMNAADRA2B | |
| SCHEMBL189975 | 0.70 | HTR1A (0.58) | HTR1AHTR2AHTR2BLMNAADRA2B | |
| Almotriptan SCHEMBL3273179 | 0.70 | HTR1A (1.00) | HTR1AHTR2AHTR2BLMNAADRA2B | |
| SCHEMBL13081207 | 0.69 | LMNA (0.66) | HTR1AHTR2AHTR2BLMNAADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104090010-A | Method for preparing electrochemical sensor for detecting almotriptan | WUXI BAILING SENSING TECHNOLOGY CO LTD | 2014-10-08 | — | — | CN | disclosed |
| CN-102106836-A | Almotriptan-containing buccal adhesive tablet as well as preparation method and application thereof | QINGDAO HUANGHAI PHARMACEUTICAL CO LTD | 2011-06-29 | — | — | CN | disclosed |