Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.80 |
| ▸ | GFER | P55789 | 1/20 | 0.80 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.80 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.53 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | IL1RN | P18510 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9345894 | 0.89 | GAA (1.00) | GAAGFERAPOBEC3GCYTH2LMNA | |
| SCHEMBL13997280 | 0.81 | CYTH2 (0.71) | GAAGFERAPOBEC3GCYTH2LMNA | |
| SCHEMBL23226678 | 0.79 | GAA (0.70) | GAAGFERAPOBEC3GHTTMEN1 | |
| SCHEMBL22112961 | 0.79 | FFAR4 (0.60) | GAAGFERAPOBEC3GLMNASMN1; SMN2 | |
| SCHEMBL8016507 | 0.78 | GAA (0.69) | GAAGFERAPOBEC3GCYTH2LMNA | |
| SCHEMBL9842326 | 0.78 | GAA (0.65) | GAAGFERAPOBEC3GCYTH2LMNA | |
| SCHEMBL7523467 | 0.78 | HSD17B3 (0.73) | GAAGFERAPOBEC3GCYTH2LMNA | |
| Acetic Acid SCHEMBL3426591 | 0.78 | CYTH2 (0.66) | GAAGFERAPOBEC3GCYTH2LMNA | |
| SCHEMBL10578347 | 0.77 | FFAR4 (0.64) | GAAGFERAPOBEC3GLMNASMN1; SMN2 | |
| SCHEMBL16366458 | 0.77 | ALDH1A1 (0.75) | GAAGFERAPOBEC3GLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102036952-A | Bis-aryl compounds for use as medicaments | BIOLIPOX AB | 2011-04-27 | — | — | CN | disclosed |