Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.33 |
| ▸ | ANPEP | P15144 | 3/20 | 0.31 |
| ▸ | LAP3 | P28838 | 2/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL29043725 | 0.74 | MMP1 (0.32) | — | |
| Iodide SCHEMBL393806 | 0.73 | — | — | |
| Bromide SCHEMBL248705 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL395146 | 0.73 | — | — | |
| Phosphoric Acid SCHEMBL3838442 | 0.73 | SLC34A1 (0.36) | TRPM8LAP3 | |
| Phosphoric Acid SCHEMBL29817339 | 0.72 | — | — | |
| Phosphoric Acid SCHEMBL7177016 | 0.70 | SLC34A1 (0.33) | TRPM8 | |
| Phosphoric Acid SCHEMBL7172949 | 0.70 | SLC34A1 (0.33) | TRPM8 | |
| Phosphoric Acid SCHEMBL28950029 | 0.69 | CYP3A4 (0.35) | TRPM8 | |
| Phosphoric Acid SCHEMBL10944058 | 0.69 | TRPM8 (0.31) | TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105647614-A | Anti-wear assembly for lubricating transmission system device and method | 路博润公司 | 2016-06-08 | — | — | CN | disclosed |
| CN-102037108-A | Antiwear composition and method for lubricating driveline components | LUBRIZOL CORP | 2011-04-27 | — | — | CN | disclosed |