Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL248705 | 0.90 | — | — | |
| Iodide SCHEMBL393806 | 0.90 | — | — | |
| SCHEMBL29190499 | 0.79 | — | — | |
| Phosphoric Acid SCHEMBL27836635 | 0.73 | TRPM8 (0.33) | — | |
| Acetic Acid SCHEMBL28592813 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL8419400 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL15771556 | 0.68 | — | — | |
| SCHEMBL1836023 | 0.64 | TSHR (0.31) | — | |
| Hydrochloric Acid SCHEMBL23905126 | 0.60 | — | — | |
| Hydrochloric Acid SCHEMBL7716994 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250326764-A1 | INHIBITORS OF THE MENIN-MLL INTERACTION | VITAE PHARMACEUTICALS LLC (US) | 2025-10-23 | — | — | US | disclosed |
| US-12312359-B2 | Inhibitors of the menin-MLL interaction | VITAE PHARMACEUTICALS, LLC (US) | 2025-05-27 | — | — | US | disclosed |
| WO-2025047582-A1 | CYCLIC OLEFIN COPOLYMER, RESIN COMPOSITION, AND MOLDED ARTICLE | ポリプラスチックス株式会社 | 2025-03-06 | — | — | WO | disclosed |
| WO-2025047583-A1 | METHOD FOR PRODUCING CYCLIC OLEFIN COPOLYMER | ポリプラスチックス株式会社 | 2025-03-06 | — | — | WO | disclosed |
| WO-2024084974-A1 | METHOD FOR PRODUCING CYCLIC OLEFIN COPOLYMER | ポリプラスチックス株式会社 | 2024-04-25 | — | — | WO | disclosed |
| US-20230391906-A1 | CYCLIC OLEFIN COPOLYMER PRODUCTION METHOD | POLYPLASTICS CO., LTD. (JP) | 2023-12-07 | — | — | US | disclosed |
| US-20230312786-A1 | PRODUCTION METHOD FOR CYCLIC OLEFIN COPOLYMER | POLYPLASTICS CO., LTD. (JP) | 2023-10-05 | — | — | US | disclosed |
| US-20230174541-A1 | INHIBITORS OF THE MENIN-MLL INTERACTION | VITAE PHARMACEUTICALS, LLC | 2023-06-08 | — | — | US | disclosed |
| CN-110950860-B | Fused tricyclic compound and application thereof in medicines | 广东东阳光药业有限公司 | 2023-03-31 | — | — | CN | disclosed |
| US-11479557-B2 | Inhibitors of the menin-MLL interaction | VITAE PHARMACEUTICALS, LLC (US) | 2022-10-25 | — | — | US | disclosed |
| US-20030060579-A1 | Catalyst component for addition polymerization, process for producing catalyst for addition polymerization and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-03-27 | — | — | US | disclosed |
| EP-1275662-A1 | MODIFIED PARTICLE, SUPPORT, CATALYST COMPONENT FOR ADDITION POLYMERIZATION, CATALYST FOR ADDITION POLYMERIZATION, AND PROCESS FOR PRODUCING ADDITION POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-01-15 | — | — | EP | disclosed |
| US-20020143124-A1 | Homogeneous type solid catalyst component or homogeneous type solid catalyst, process for production thereof and process for producing addition polymer with the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-10-03 | — | — | US | disclosed |
| US-20010020075-A1 | Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-09-06 | — | — | US | disclosed |
| EP-1113026-A2 | Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-07-04 | — | — | EP | disclosed |
| EP-1051461-A2 | FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE | ORR, William C. (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999066009-A2 | FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE | ORR WILLIAM C (US) | 1999-12-23 | — | — | WO | disclosed |
| EP-0954558-A1 | FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY | ORR, William C. (US) | 1999-11-10 | — | — | EP | disclosed |
| WO-1998026028-A1 | FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY | ORR WILLIAM C (US) | 1998-06-18 | — | — | WO | disclosed |
| US-5591754-A | Benzoylguanidines, pharmaceutical composition containing them and treatment of arrthythmias therewith | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-01-07 | — | — | US | disclosed |