⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30969096 | 0.92 | — | — | |
| SCHEMBL400292 | 0.86 | TBXAS1 (0.33) | — | |
| SCHEMBL809437 | 0.86 | TBXAS1 (0.33) | — | |
| SCHEMBL403240 | 0.82 | CD81 (0.33) | — | |
| SCHEMBL1802297 | 0.81 | TBXAS1 (0.31) | — | |
| SCHEMBL8466019 | 0.79 | TBXAS1 (0.32) | — | |
| SCHEMBL1803466 | 0.79 | TBXAS1 (0.32) | — | |
| SCHEMBL30720429 | 0.79 | TSHR (0.39) | — | |
| SCHEMBL15535508 | 0.79 | CD81 (0.39) | — | |
| SCHEMBL2474722 | 0.77 | TDP1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3861039-B1 | HYDROGEL COMPOSITIONS | OPHTALMIC CIE (FR) | 2023-11-01 | — | — | EP | claimed |
| EP-2077292-B1 | Polysiloxane-based prepolymer and hydrogel | FAR EASTERN NEW CENTURY CORP (TW) | 2013-08-14 | — | — | EP | claimed |
| US-10795058-B2 | Silicone-based hydrophilic copolymer and hydrogel compositions comprising the same | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2020-10-06 | — | — | US | disclosed |
| US-20180120480-A1 | SILICONE-BASED HYDROPHILIC COPOLYMER AND HYDROGEL COMPOSITIONS COMPRISING THE SAME | MOMENTIVE PERFORMANCE MATERIALS INC. | 2018-05-03 | — | — | US | disclosed |
| US-9944742-B2 | Organo-modified silicone polymers | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2018-04-17 | — | — | US | disclosed |
| US-9890234-B2 | Organo-modified silicone polymers and hydrogels comprising the same | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2018-02-13 | — | — | US | disclosed |
| EP-3274384-A1 | VINYL-BASED SILICONE-SUBSTITUTED HYDROPHILIC COPOLYMER AND HYDROGEL COMPOSITION COMPRISING THE SAME | Momentive Performance Materials Inc. (US) | 2018-01-31 | — | — | EP | disclosed |
| US-9851472-B2 | Silicone-based hydrophilic copolymer and hydrogel compositions comprising the same | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2017-12-26 | — | — | US | disclosed |
| WO-2016160488-A1 | VINYL-BASED SILICONE-SUBSTITUTED HYDROPHILIC COPOLYMER AND HYDROGEL COMPOSITION COMPRISING THE SAME | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2016-10-06 | — | — | WO | disclosed |
| US-20160282517-A1 | SILICONE-BASED HYDROPHILIC COPOLYMER AND HYDROGEL COMPOSITIONS COMPRISING THE SAME | MOMENTIVE PERFORMANCE MATERIALS INC. | 2016-09-29 | — | — | US | disclosed |
| EP-2838955-A2 | ORGANO-MODIFIED SILICONE POLYMERS | Momentive Performance Materials Inc. (US) | 2015-02-25 | — | — | EP | disclosed |
| EP-2828338-A2 | ORGANO-MODIFIED SILICONE POLYMERS AND HYDROGELS COMPRISING THE SAME | Momentive Performance Materials Inc. (US) | 2015-01-28 | — | — | EP | disclosed |
| US-20150011788-A1 | ORGANO-MODIFIED SILICONE POLYMERS | MOMENTIVE PERFORMANCE MATERIALS INC. | 2015-01-08 | — | — | US | disclosed |
| US-20150011671-A1 | ORGANO-MODIFIED SILICONE POLYMERS AND HYDROGELS COMPRISING THE SAME | MOMENTIVE PERFORMANCE MATERIALS INC. | 2015-01-08 | — | — | US | disclosed |
| WO-2013142055-A2 | ORGANO-MODIFIED SILICONE POLYMERS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2013-09-26 | — | — | WO | disclosed |
| WO-2013142052-A2 | ORGANO-MODIFIED SILICONE POLYMERS AND HYDROGELS COMPRISING THE SAME | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2013-09-26 | — | — | WO | disclosed |
| US-8383745-B2 | Method for producing N-methyl-N-vinylacetamide having improved stability and polymerizability | SHOWA DENKO K.K. (JP) | 2013-02-26 | — | — | US | disclosed |
| US-20100280204-A1 | METHOD FOR PRODUCING N-METHYL-N-VINYLACETAMIDE HAVING IMPROVED STABILITY AND POLYMERIZABILITY | SHOWA DENKO K.K. (JP) | 2010-11-04 | — | — | US | disclosed |
| EP-2239250-A1 | METHOD FOR PRODUCING N-METHYL-N-VINYLACETAMIDE HAVING IMPROVED STABILITY AND POLYMERIZABILITY | Showa Denko K.K. (JP) | 2010-10-13 | — | — | EP | disclosed |